Molecular and Physicochemical Properties Impacting OralAbsorptionofDrugs

  • Wei-Qin (Tony) Tong

Oral administration is still regarded as the most commonly accepted route of drug administration offering numerous advantages including convenience, ease of compliance, and cost-effectiveness. Not surprisingly, desirable oral bioavailability is one of the most important considerations for the successful development of bioactive molecules. Poor oral bioavailability affects drug performance and leads to high intra- and inter-patient variability.


Dissolution Rate Bile Salt Oral Bioavailability Solid Dispersion Oral Absorption 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Wei-Qin (Tony) Tong
    • 1
  1. 1.Novartis Pharmaceuticals CorporationEast HanoverUSA

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