Bioengineering and the Ovarian Follicle
Three-dimensional scaffolds are widely used in the field of tissue engineering, which combines the principles and methods of the life sciences with those of engineering to provide a fundamental understanding of structure–function relationships in normal and diseased tissues, to develop materials and methods to repair damaged or diseased tissues, and to create entire tissue replacements . A synthetic scaffold can serve as a stroma that creates a cellular environment designed to provide the factors that stimulate maturation of ovarian follicles, but lacks the factors found in the native stroma that inhibit follicle maturation.
KeywordsGranulosa Cell Ovarian Follicle Primordial Follicle Mouse Oocyte Follicle Development
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