Bioengineering and the Ovarian Follicle

  • Min Xu
  • Teresa K. Woodruff
  • Lonnie D. Shea
Part of the Cancer Treatment and Research book series (CTAR, volume 138)

Three-dimensional scaffolds are widely used in the field of tissue engineering, which combines the principles and methods of the life sciences with those of engineering to provide a fundamental understanding of structure–function relationships in normal and diseased tissues, to develop materials and methods to repair damaged or diseased tissues, and to create entire tissue replacements [1]. A synthetic scaffold can serve as a stroma that creates a cellular environment designed to provide the factors that stimulate maturation of ovarian follicles, but lacks the factors found in the native stroma that inhibit follicle maturation.


Granulosa Cell Ovarian Follicle Primordial Follicle Mouse Oocyte Follicle Development 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Min Xu
    • 1
  • Teresa K. Woodruff
    • 2
  • Lonnie D. Shea
    • 3
  1. 1.Northwestern UniversityChicagoUSA
  2. 2.Institute for Women's Health Research, Feinberg School of MedicineNorthwestern UniversityChicagoUSA
  3. 3.Northwestern UniversityChicagoUSA

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