Cancer is often considered a disease of aging, and many times it is, as the risk of malignancy increases with age. In fact, according to the American Cancer Society, 77% of all cancers are diagnosed in patients older than age 55 [1]. However, it is not a disease isolated to the older population alone. Any person can develop cancer; it targets children and young adults, and it does not discriminate by gender, race, socioeconomic status, political belief, or religious affiliation. Data collected from the National Cancer Institute (NCI) registry of cancer patients estimated that there were 10,500,000 survivors of cancer in 2003 and roughly 1,440,000 new cancer cases are expected to be diagnosed in 2007 (see Fig. 16.1). Among survivors, 5% are between 20 and 39 years old, resulting in at least 525,000 young survivors of cancer, a number that increases every year. More than 200,000 men and women under the age of 45 are diagnosed with cancer annually. Moreover, 25% of breast cancer patients are younger than 40 years of age. Though over 12,400 children and adolescents (less than 19 years old) are diagnosed with cancer each year, the cure rate for all childhood cancers has reached 80 % [2]. While this is a remarkable statistic, the improvement in survival reflects progress in earlier detection of certain malignancies and the extraordinary rise in cancer curing therapies.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
American Cancer Society. Cancer facts and figures 2007. Atlanta: American Cancer Society, 2007.
National Cancer Institute. Cancer Survivorship Research–2005. Bethesda, MD: National Cancer Institute, 2005.
Lee SJ, Schover LR, Partridge AH, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006;24:2917–2931.
Wallace WH, Thomson AB, Kelsey TW. The radiosensitivity of the human oocyte. Hum Reprod 2003;18:117–121.
Wallace WH, Thomson AB, Saran F, et al. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys 2005;62:738–744.
Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: Who is at risk and what can be offered? Lancet 2005;6:209–218.
Bleyer WA. The impact of childhood cancer on the United States and the world. CA Cancer J Clin 1990;40:355–367.
Reiss U, Cowan M, McMillan A, et al. Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors, and outcome in a cohort of 241 patients. J Pediatr Hematol Oncol 2002;24:746–750.
Bleyer WA. The U.S. pediatric cancer clinical trials programmes: International implications and the way forward. Eur J Cancer 1997;33:1439–1447.
Bhatia S, Meadows AT. Long-term follow-up of childhood cancer survivors: future directions for clinical care and research. Pediatr Blood Cancer 2006;46:143–148.
Eiser C. Practitioner review: long-term consequences of childhood cancer. J Child Psychol Psychiatry 1998;39:621–633.
Eiser C. Repressive adaptation in children with cancer: It may be better not to know. Child Care Health Dev 1998;24:243–244.
Kopel SJ, Eiser C, Cool P, et al. Brief report: Assessment of body image in survivors of childhood cancer. J Pediatr Psychol 1998;23:141–147.
Zeltzer LK. Cancer in adolescents and young adults psychosocial aspects. Long-term survivors. Cancer 1993;71:3463–3468.
Stevens MC, Mahler H, Parkes S. The health status of adult survivors of cancer in childhood. Eur J Cancer 1998;34:694–698.
Crockin SL. The “embryo” wars: at the epicenter of science, law, religion, and politics. Fam Law Q 2005;39:599–632.
Crockin SL. Reproduction, genetics and the law. Reprod Biomed Online 2005;10:692–704.
Crockin SL. Legal issues related to parenthood after cancer. J Natl Cancer Inst Monogr 2005;34:111–113.
Patrizio P, Butts S, Caplan A. Ovarian tissue preservation and future fertility: emerging technologies and ethical considerations. J Natl Cancer Inst Monogr 2005;34:107–110.
Robertson JA. Cancer and fertility: ethical and legal challenges. J Natl Cancer Inst Monogr 2005;34:104–106.
Schover LR, Brey K, Lichtin A, et al. Oncologists’ attitudes and practices regarding banking sperm before cancer treatment. J Clin Oncol 2002;20:1890–1897.
The Ethics Committee of the American Society for Reproductive Medicine. Fertility preservation and reproduction in cancer Patients. Fertil Steril 2005;83:1622–1628.
American Society of Reproductive Medicine Mission Statement. Birmingham: American Society of Reproductive Medicine, 2005.
Waljee A, Waljee J, Morris AM, et al. Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis. Gut 2006; 55:1575–1580.
Janssen NM, Genta MS. The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation. Arch Intern Med 2000;160:610–619.
Holley JL. The hypothalamic–pituitary axis in men and women with chronic kidney disease. Adv Chronic Kidney Dis 2004;11:337–341.
Kelly-Weeder S, O’Connor A. Modifiable risk factors for impaired fertility in women: what nurse practitioners need to know. J Am Acad Nurse Pract 2006;18:268–276.
Boomsma CM, Eijkemans MJ, Hughes EG, et al. A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome. Hum Reprod Update 2006;12:673–683.
Jordan C, Revenson TA. Gender differences in coping with infertility: A meta-analysis. J Behav Med 1999;22:341–358.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Kondapalli, L.A. (2007). Oncofertility: A New Medical Discipline and the Emerging Scholar. In: Woodruff, T.K., Snyder, K.A. (eds) Oncofertility Fertility Preservation for Cancer Survivors. Cancer Treatment and Research, vol 138. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72293-1_16
Download citation
DOI: https://doi.org/10.1007/978-0-387-72293-1_16
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-72292-4
Online ISBN: 978-0-387-72293-1
eBook Packages: MedicineMedicine (R0)