Skip to main content

Oncofertility: A New Medical Discipline and the Emerging Scholar

  • Chapter

Part of the book series: Cancer Treatment and Research ((CTAR,volume 138))

Cancer is often considered a disease of aging, and many times it is, as the risk of malignancy increases with age. In fact, according to the American Cancer Society, 77% of all cancers are diagnosed in patients older than age 55 [1]. However, it is not a disease isolated to the older population alone. Any person can develop cancer; it targets children and young adults, and it does not discriminate by gender, race, socioeconomic status, political belief, or religious affiliation. Data collected from the National Cancer Institute (NCI) registry of cancer patients estimated that there were 10,500,000 survivors of cancer in 2003 and roughly 1,440,000 new cancer cases are expected to be diagnosed in 2007 (see Fig. 16.1). Among survivors, 5% are between 20 and 39 years old, resulting in at least 525,000 young survivors of cancer, a number that increases every year. More than 200,000 men and women under the age of 45 are diagnosed with cancer annually. Moreover, 25% of breast cancer patients are younger than 40 years of age. Though over 12,400 children and adolescents (less than 19 years old) are diagnosed with cancer each year, the cure rate for all childhood cancers has reached 80 % [2]. While this is a remarkable statistic, the improvement in survival reflects progress in earlier detection of certain malignancies and the extraordinary rise in cancer curing therapies.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. American Cancer Society. Cancer facts and figures 2007. Atlanta: American Cancer Society, 2007.

    Google Scholar 

  2. National Cancer Institute. Cancer Survivorship Research–2005. Bethesda, MD: National Cancer Institute, 2005.

    Google Scholar 

  3. Lee SJ, Schover LR, Partridge AH, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006;24:2917–2931.

    Article  PubMed  Google Scholar 

  4. Wallace WH, Thomson AB, Kelsey TW. The radiosensitivity of the human oocyte. Hum Reprod 2003;18:117–121.

    Article  PubMed  CAS  Google Scholar 

  5. Wallace WH, Thomson AB, Saran F, et al. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys 2005;62:738–744.

    PubMed  Google Scholar 

  6. Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: Who is at risk and what can be offered? Lancet 2005;6:209–218.

    Article  Google Scholar 

  7. Bleyer WA. The impact of childhood cancer on the United States and the world. CA Cancer J Clin 1990;40:355–367.

    Article  PubMed  CAS  Google Scholar 

  8. Reiss U, Cowan M, McMillan A, et al. Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors, and outcome in a cohort of 241 patients. J Pediatr Hematol Oncol 2002;24:746–750.

    Article  PubMed  Google Scholar 

  9. Bleyer WA. The U.S. pediatric cancer clinical trials programmes: International implications and the way forward. Eur J Cancer 1997;33:1439–1447.

    Article  PubMed  CAS  Google Scholar 

  10. Bhatia S, Meadows AT. Long-term follow-up of childhood cancer survivors: future directions for clinical care and research. Pediatr Blood Cancer 2006;46:143–148.

    Article  PubMed  Google Scholar 

  11. Eiser C. Practitioner review: long-term consequences of childhood cancer. J Child Psychol Psychiatry 1998;39:621–633.

    Article  PubMed  CAS  Google Scholar 

  12. Eiser C. Repressive adaptation in children with cancer: It may be better not to know. Child Care Health Dev 1998;24:243–244.

    PubMed  CAS  Google Scholar 

  13. Kopel SJ, Eiser C, Cool P, et al. Brief report: Assessment of body image in survivors of childhood cancer. J Pediatr Psychol 1998;23:141–147.

    Article  PubMed  CAS  Google Scholar 

  14. Zeltzer LK. Cancer in adolescents and young adults psychosocial aspects. Long-term survivors. Cancer 1993;71:3463–3468.

    Article  PubMed  CAS  Google Scholar 

  15. Stevens MC, Mahler H, Parkes S. The health status of adult survivors of cancer in childhood. Eur J Cancer 1998;34:694–698.

    Article  PubMed  CAS  Google Scholar 

  16. Crockin SL. The “embryo” wars: at the epicenter of science, law, religion, and politics. Fam Law Q 2005;39:599–632.

    PubMed  Google Scholar 

  17. Crockin SL. Reproduction, genetics and the law. Reprod Biomed Online 2005;10:692–704.

    Article  PubMed  Google Scholar 

  18. Crockin SL. Legal issues related to parenthood after cancer. J Natl Cancer Inst Monogr 2005;34:111–113.

    Article  PubMed  Google Scholar 

  19. Patrizio P, Butts S, Caplan A. Ovarian tissue preservation and future fertility: emerging technologies and ethical considerations. J Natl Cancer Inst Monogr 2005;34:107–110.

    Article  PubMed  Google Scholar 

  20. Robertson JA. Cancer and fertility: ethical and legal challenges. J Natl Cancer Inst Monogr 2005;34:104–106.

    Article  PubMed  Google Scholar 

  21. Schover LR, Brey K, Lichtin A, et al. Oncologists’ attitudes and practices regarding banking sperm before cancer treatment. J Clin Oncol 2002;20:1890–1897.

    Article  PubMed  Google Scholar 

  22. The Ethics Committee of the American Society for Reproductive Medicine. Fertility preservation and reproduction in cancer Patients. Fertil Steril 2005;83:1622–1628.

    Article  Google Scholar 

  23. American Society of Reproductive Medicine Mission Statement. Birmingham: American Society of Reproductive Medicine, 2005.

    Google Scholar 

  24. Waljee A, Waljee J, Morris AM, et al. Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis. Gut 2006; 55:1575–1580.

    Article  PubMed  CAS  Google Scholar 

  25. Janssen NM, Genta MS. The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation. Arch Intern Med 2000;160:610–619.

    Article  PubMed  CAS  Google Scholar 

  26. Holley JL. The hypothalamic–pituitary axis in men and women with chronic kidney disease. Adv Chronic Kidney Dis 2004;11:337–341.

    Article  PubMed  Google Scholar 

  27. Kelly-Weeder S, O’Connor A. Modifiable risk factors for impaired fertility in women: what nurse practitioners need to know. J Am Acad Nurse Pract 2006;18:268–276.

    Article  PubMed  Google Scholar 

  28. Boomsma CM, Eijkemans MJ, Hughes EG, et al. A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome. Hum Reprod Update 2006;12:673–683.

    Article  PubMed  CAS  Google Scholar 

  29. Jordan C, Revenson TA. Gender differences in coping with infertility: A meta-analysis. J Behav Med 1999;22:341–358.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Kondapalli, L.A. (2007). Oncofertility: A New Medical Discipline and the Emerging Scholar. In: Woodruff, T.K., Snyder, K.A. (eds) Oncofertility Fertility Preservation for Cancer Survivors. Cancer Treatment and Research, vol 138. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72293-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-72293-1_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-72292-4

  • Online ISBN: 978-0-387-72293-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics