A Brief History of Research on Agrobacterium Tumefaciens: 1900–1980s

  • Andrew N. Binns

The study of tumorigenesis on plants as a result of their infection by Agrobacterium tumefaciens has resulted in enormous advances in our understanding of interspecies genetic transfer. This chapter seeks to trace the earlier studies (from the early 1900s up to mid 1980s) that were involved in defining the biology, genetics and molecular biology of this system. The analysis of these studies will be carried out with the objective of unders-tanding how Agrobacterium has become not only a model system in bacterial pathogenesis but also a key player in both basic plant molecular genetics and agricultural biotechnology.


Agrobacterium Tumefaciens Crown Gall Agrobacterium Rhizogenes Crown Gall Tumor Crown Gall Disease 


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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Andrew N. Binns
    • 1
  1. 1.Department of Biology and Plant Sciences InstituteUniversity of PennsylvaniaPhiladelphiaUSA

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