Insulin Action Gene Regulation

  • Calum Sutherland
  • Richard M. O’ Brien
  • Daryl K. Granner


Insulin regulates metabolism by altering the concentration of critical proteins or by inducing post-translational modifications of preexisting molecules. The latter represents a well-recognized action of insulin, and it has been extensively studied for many years.1, 2, 3By contrast, it is only recently that considerable advances have been made in understanding several aspects of insulin-regulated gene expression.


Insulin Action Insulin Receptor Substrate Fatty Acid Synthetase H4IIE Cell Insulin Regulation 


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2007

Authors and Affiliations

  • Calum Sutherland
  • Richard M. O’ Brien
  • Daryl K. Granner
    • 1
  1. 1.Department of Molecular Physiology and BiophysicsVanderbilt University Medical SchoolNashvilleUSA

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