Invasion and Dissemination of Yersinia enterocolitica in the Mouse Infection Model

  • Konrad Trülzsch
  • Jürgen Heesemann
  • Mark F. Oellerich
Part of the Advances In Experimental Medicine And Biology book series (AEMB, volume 603)

Yersinia enterocolitica is one of the most common causes of food borne gastrointestinal disease. After oral uptake yersiniae replicate in the small intestine, invade Peyeŕs patches of the distal ileum and disseminate to spleen and liver. In these tissues and organs yersiniae replicate extracellularly and form exclusively monoclonal microabscesses. Only very few yersiniae invade Peyeŕs patches and establish just a very few monoclonal microabscesses. This is due to both Yersinia and host specific factors.


Mesenteric Lymph Node Distal Ileum Yersinia Enterocolitica Oral Infection Mouse Infection Model 
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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Konrad Trülzsch
    • 1
  • Jürgen Heesemann
    • 1
  • Mark F. Oellerich
    • 1
  1. 1.Max von Pettenkofer Institute for Hygiene and Medical MicrobiologyLudwig Maximillians UniversityGermany

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