Yersinia enterocolitica has two type III secretion systems (TTSS): The well characterized Ysc-Yop system and the relatively uncharacterized Ysa-Ysp system. Detection of Ysps in culture supernatants has only been observed in vitro when cultures are grown at low temperature (26°C) and in high salt (290mM NaCl). Previous reports demonstrated that expression from the ysaE promoter was activated by high salt. In this study, we report a new environmental stimulus for ysa gene expression; in the presence of high salt, growth on solid surface stimulates expression 7-fold compared to growth in high salt broth. These new data indicate that, in the presence of salt, solid surface is an extremely robust signal for the Ysa system.
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Mildiner-Earley, S., Miller, V.L., Walker, K.A. (2007). Environmental Stimuli Affecting Expression of the Ysa Type Three Secretion Locus. In: Perry, R.D., Fetherston, J.D. (eds) The Genus Yersinia. Advances In Experimental Medicine And Biology, vol 603. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72124-8_18
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DOI: https://doi.org/10.1007/978-0-387-72124-8_18
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