Sarcomatoid Carcinoma: Pleomorphic Carcinoma, Spindle Cell Carcinoma, Giant Cell Carcinoma, Carcinosarcoma, and Pulmonary Blastoma

  • Philip Hasleton


The 2004 World Health Organization (WHO) classification of lung tumors1 defines sarcomatoid carcinomas as a group of poorly differentiated, non-small-cell lung carcinomas that contain a component of sarcoma or sarcomalike (spindle or giant cell) differentiation. Five subgroups are currently recognized: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma, and pulmonary blastoma. These entities have been considered separately previously. The WHO does not recommend the use of the terms homologous or heterologous, as proposed by Wick et al.2 These tumors are rare, accounting for approximately between 0.3% and 1.3% of all lung malignancies.1


Giant Cell Sarcomatoid Carcinoma Pleomorphic Carcinoma Pulmonary Blastoma Giant Cell Carcinoma 


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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Philip Hasleton
    • 1
  1. 1.Department of Histopathology, Clinical Sciences BlockManchester Royal InfirmaryManchesterUK

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