This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Poirier J (1994) Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. TINS 17:525–530
Elshourbagy NA, Liao WS, Mahley RW, Taylor JM (1985) Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc Natl Acad Sci U S A 82:203–207
Poirier J (2003) Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends Mol Med 9:94–101
Castillo M, Zafra MF, Garcia-Peregrin E (1988) Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia. Neurochem Res 13:551–555
Shefer S, Tint GS, Jean-Guillaume D, et al (2000) Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and forebrain pathology in the PKU mouse? J Neurosci Res 61:549–563
Toews AD, Roe EB, Goodrum JF, et al (1997) Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. Mol Brain Res 49:113–119
LaDu MJ, Gilligan SM, Lukens JR, et al (1998) Nascent astrocyte particles differ from lipoproteins in CSF. J Neurochem 70:2070–2081
Utermann G, Langenbeck U, Beisiegel U, Weber W (1980) Genetics of the apolipoprotein E system in man. Am J Hum Genet 32:339–347
Davignon J, Gregg RE, Sing CF (1988) Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 8:1–21
Arendt T, Schindler C, Bruckner MK, et al (1997) Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. J Neurosci 17:516–529
Ji Y, Gong Y, Gan W, et al (2003a) Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients. Neuroscience 122:305–315
Ji Y, Gong Y, Gan W, et al (2003b) Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients. Neuroscience 122:305–315
Poirier J, Delisle MC, Quirion R, et al (1995) Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proc Natl Acad Sci USA 92:12260–12264
Poirier J, Davignon J, Bouthillier D, et al (1993b) Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342:697–699
Strittmatter WJ, Saunders AM, Schmechel D, et al (1993) Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 90:1977–1981
Brown MS, Goldstein JL, Siperstein MD (1973) Regulation of cholesterol synthesis in normal and malignant tissue. Fed Proc 32:2168–2173
Boyles JK, Zoellner CD, Anderson LJ, et al (1989) A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J Clin Invest 83:1015–1031
Poirier J, Hess M, May PC, Finch CE (1991) Astrocytic apolipoprotein E messenger-RNA and GFAP messenger-RRNA in hippocampus after entorhinal cortex lesioning. Mol Brain Res 11:97–106
Poirier J, Baccichet A, Dea D, Gauthier S (1993a) Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience 55:81–90
Aleong R, Aumont N, Dea D, Poirier J (2003) Non-steroidal anti-inflammatory drugs mediate increased in vitro glial expression of apolipoprotein E protein. Eur J Neurosci 18:1428–1438
Jick H, Zornberg GL, Jick SS, et al (2000) Statins and the risk of dementia. Lancet 356:1627–1631
Rockwood K, Kirkland S, Hogan SB, et al (2002) Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol 59:223–227
Wolozin B, Kellman W, Ruosseau P, et al (2000) Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57:1439–1443
Wagstaff LR, Mitton MW, Arvik BM,. Doraiswamy PM (2003) Statin-associated memory loss: analysis of 60 case reports and review of the literature. Pharmacotherapy 23:871–880
Zamrini E, McGwin G, Roseman JM (2004) Association between statin use and Alzheimer's disease. Neuroepidemiology 23:94–98.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer Science+Business Media, LLC
About this paper
Cite this paper
Poirier, J., Lamarre-Théroux, L., Dea, D., Aumont, N., Blain, J.F. (2008). Cholesterol Transport and Production in Alzheimer’s Disease. In: Fisher, A., Memo, M., Stocchi, F., Hanin, I. (eds) Advances in Alzheimer’s and Parkinson’s Disease. Advances in Behavioral Biology, vol 57. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72076-0_21
Download citation
DOI: https://doi.org/10.1007/978-0-387-72076-0_21
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-72074-6
Online ISBN: 978-0-387-72076-0
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)