Introduction: The Emergence of Nanoparticles as Imaging Platform in Biomedicine

  • Jeff. W.M. Bulte
  • Michel M.J. Modo
Part of the Fundamental Biomedical Technologies book series (FBMT, volume 102)


Nanoparticles have now emerged as widely used diagnostic agents in biomedicine. They possess unique features that can be exploited with imaging. Among these are an increased sensitivity in detection through amplification of signal changes; a manipulation of surface structures and enhancement of uptake by selected cells (macrophages); altered pharmacokinetics allowing, for instance, their use as blood pool imaging agents; and physicochemical manipulations of energy (i.e., quantum dots). Specific aspects of nanoparticles are introduced to illustrate their use in biomedical imaging.


Contrast Agent Myocardial Perfusion Imaging Colloidal Gold Biomedical Imaging Chemical Exchange Saturation Transfer 
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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Jeff. W.M. Bulte
  • Michel M.J. Modo

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