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Mycobacterial Infections in Primary Immunodeficiency Patients

  • Elizaveta Galkina
  • Irina Kondratenko
  • Andrey Bologov
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 601)

Abstract

Primary immunodeficiencies (PID) are a diverse group of hereditary diseases leading to the impaired immune response that creates high susceptibility to mycobacterium infection. High susceptibility to mycobacterial infections of patients suffering from defects of phagocytosis and combined immunodeficiencies can be explained by predominant participation of macrophages and T lymphocytes in the specific immune response. Mycobacterium tuberculosis, Bacille Calmette-Guerin, and non-tuberculosis mycobacterium (NTM) may cause a severe disease in patients with PIDs. We report here our results of the clinical features of mycobacterium infection presentations in 36 patients with various PIDs.

Keywords

Chronic Granulomatous Disease Mycobacterial Infection Severe Combine Immunodeficiency Common Variable Immunodeficiency Nijmegen Breakage Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Elizaveta Galkina
    • 1
  • Irina Kondratenko
    • 1
  • Andrey Bologov
    • 1
  1. 1.Russian Clinical Children’s HospitalMoscowRussia

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