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Memory T Cells in Allograft Rejection

  • Anna Valujskikh
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 601)

Abstract

T cell repertoire of many humans contains high frequencies of memory T cells specific for alloantigens. The increasing evidence implicates these cells as a barrier to allograft survival and to the induction of transplantation tolerance. This review discusses several aspects of memory T cell immunobiology pertinent to their role in transplantation.

Keywords

Allograft Rejection Allograft Survival Secondary Lymphoid Organ S1P1 Receptor Costimulatory Pathway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Department of ImmunologyThe Cleveland Clinic FoundationClevelandUSA

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