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Natural Killer T (NKT) Cell Subsets in Chlamydial Infections

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 601)

Abstract

Natural killer T (NKT) cells are a newly identified unique subset of cells that express both α β T cell receptor and NK cell markers. We investigated the role of NKT cells in modulating adaptive T cell responses in chlamydial infections using human-disease-related chlamydial species. Our study provides in vivo evidence that even closely related pathogens may activate different functional NKT subsets, which can further polarize CD4+ and CD8+ cells in adaptive immune responses.

Keywords

Chlamydial Infection Intracellular Cytokine Staining Cytokine Pattern Related Pathogen CD1d Tetramer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Laboratory for Infection and Immunity, Departments of Medical Microbiology and ImmunologyUniversity of ManitobaWinnipegCanada

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