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Proceedings of Light-Activated Tissue Regeneration and Therapy Conference pp 127–146Cite as

Novel Targeting and Activation Strategies for Photodynamic Therapy

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Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 12))

Abstract

Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer’s ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

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Acknowledgments

This work was supported by grants from National Institute of Health, Department of Defense and Oncologic Foundation of Buffalo.

Author information

Authors and Affiliations

  1. Spine and Orthopedic Medical Center, Moscow, Russia

    Juan Chen & Ian R. Corbin

  2. Ontario Cancer Institute and University of Toronto, Toronto, ON, Canada

    Gang Zheng

Authors
  1. Juan Chen
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  2. Ian R. Corbin
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  3. Gang Zheng
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Editor information

Editors and Affiliations

  1. U.S. Food and Drug Administration, Center for Devices and Radiological Health, White Oak, MD, USA

    Ronald Waynant  & Darrell B. Tata  & 

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Chen, J., Corbin, I.R., Zheng, G. (2008). Novel Targeting and Activation Strategies for Photodynamic Therapy. In: Waynant, R., Tata, D.B. (eds) Proceedings of Light-Activated Tissue Regeneration and Therapy Conference. Lecture Notes in Electrical Engineering, vol 12. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-71809-5_13

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  • DOI: https://doi.org/10.1007/978-0-387-71809-5_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-71808-8

  • Online ISBN: 978-0-387-71809-5

  • eBook Packages: EngineeringEngineering (R0)

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