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Actin-Binding Proteins and Disease pp 16–36Cite as

Actin Genetic Diseases

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Part of the book series: Protein Reviews ((PRON,volume 8))

The human genome, as for other mammals, contains six actin genes, ACTA1, ACTA2, ACTB, ACTC, ACTG1, and ACTG2. Four of these genes are differentially expressed in cardiac (ACTC), smooth (ACTA2), enteric (ACTG2), and skeletal muscles (ACTA1); two are described as cytoplasmic actin genes (ACTB and ACTG1) and are expressed in all cells.

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Authors and Affiliations

  1. Department of Biology, University of York, York, YO10 5DD, UK

    John C. Sparrow

  2. Centre for Medical Research, University of Western Australia, Western Australian Institute for Medical Research, QEII Medical Centre, Nedlands, Western Australia, 6009, Australia

    Nigel G. Laing

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  1. John C. Sparrow
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  2. Nigel G. Laing
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Editors and Affiliations

  1. Muscle Research Unit Bosch Institute, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia

    Cristobal G. dos Remedios

  2. Discipline of Anatomy and Histology Bosch Institute, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia

    Deepak Chhabra

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Sparrow, J.C., Laing, N.G. (2008). Actin Genetic Diseases. In: dos Remedios, C.G., Chhabra, D. (eds) Actin-Binding Proteins and Disease. Protein Reviews, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-0-387-71749-4_2

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