The Rationale for Glutamatergic Therapy in Alzheimer's Disease
Glutamate is the primary excitatory neurotransmitter of the central nervous system and is used by approximately two-thirds of synapses in the neocortex and hippocampus while acetylcholine is found in perhaps 5% such synapses (Danbolt, 2001; Fonnum, 1984).
KeywordsNMDA Receptor AMPA Receptor Glutamate Transporter Glutamatergic System Synapse Loss
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