Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs

  • Benjamin Wolozin

Epidemiological studies have identified numerous existing medications that appear to be associated with a reduced incidence or progression of Alzheimer’s disease. The literature surrounding these studies is confusing because of conflicting data. Retrospective epidemiological studies of both statins and nonsteroidal anti-inflammatory drugs (NSAIDs) show an association between medication use and a reduced incidence or progression of AD (Breitner et al., 1994; Jick, Zornberg, Jick, Seshadri, & Drachman, 2000; Wolozin, Kellman, Ruosseau, Celesia, & Siegel, 2000).


Alzheimer Disease Statin Treatment Health Care Database Health Care Record Retrospective Epidemiological Study 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Benjamin Wolozin
    • 1
  1. 1.Department of PharmacologyBoston University School of MedicineBostonUSA

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