HIV-Related Research with Cognitively Impaired Persons

  • Sana Loue
  • Earl C. Pike


Human Immunodeficiency Virus Human Immunodeficiency Virus Infection Severe Mental Illness Human Immunodeficiency Virus Prevention Serious Mental Illness 
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  1. Advisory Committee on Human Radiation Experiments. (1996). Final Report. Washington, D.C: The Committee.Google Scholar
  2. American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, D.C.: Author.Google Scholar
  3. Annas, G.J., & Glantz, L.H. (1997). Informed consent to research on institutionalized mentally disabled persons: The dual problems of incapacity and voluntariness. In A.E. Shamoo (Ed.), Ethics in Neurobiological Research with Human Subjects: The Baltimore Conference on Ethics (pp. 55–79). Amsterdam: Gordon and Breach Publishers.Google Scholar
  4. Backlar, P. (1998). Anticipatory planning for research participants with psychotic disorders like schizophrenia. Psychology, Public Policy, and Law, 4, 829–848.PubMedCrossRefGoogle Scholar
  5. Barker, P.R. et al. (1992). Serious mental illness and disability in the adult household population: United States, 1989. In R.W. Manderscheid, M.A. Sonnenschein (Eds.), Advance Data from Vital and Health Statistics of the National Center for Health Statistics, No. 218. Washington, D.C.: Department of Health and Human Services.Google Scholar
  6. Beauchamp, T.L., Jennings, B., Kinney, E.D., & Levine, R.J. (2002). Pharmaceutical research involving the homeless. Journal of Medicine and Philosophy, 27(5), 547–564.PubMedCrossRefGoogle Scholar
  7. Bein, P.M. (1991). Surrogate consent and the incompetent experimental subject. Food, Drug, & Cosmetic Law Journal, 46(5), 739–771.Google Scholar
  8. Benson, P.R., Roth, L.H., Appelbaum, P.S., Lidz, C.W., & Winslade, W.J. (1988). Informa-tion disclosure, subject understanding, and informed consent in psychiatric research. Law and Human Behavior, 12(4), 455–475.PubMedCrossRefGoogle Scholar
  9. Bergler, J.H.., Pennington, A.C., Metcalfe, M., & Freis, E.D. (1980). Informed consent: How much does the patient understand? Clinical Pharmacology & Therapeutics, 27, 435–440.CrossRefGoogle Scholar
  10. Bisbing, S., McMenamin, J., & Granville, R. (1995). Competency, capacity, and immunity. In ACLM Textbook Committee (Ed.), Legal Medicine, 3rd edition (pp. 27–45). St. Louis, Missouri: Mosby-Year Book.Google Scholar
  11. Bloch, S., Chodoff, P., & Green, S. (Eds.). (1999). Psychiatric Ethics. New York: Oxford University Press.Google Scholar
  12. Bonnie, R.J. (1997). Research with cognitively impaired subjects: Unfinished business in the regulation of human research. Archives of General Psychiatry, 54(2), 105–111.PubMedGoogle Scholar
  13. Carey, M.P., Carey K.B., & Kalichman, S.C. (1997). Risk for human immunodeficiency virus (HIV) infection among persons with severe mental illnesses. Clinical Psychology Review, 17, 271–291.PubMedCrossRefGoogle Scholar
  14. Carey, M.P., Weinhardt, L.S., & Carey, K.B. (1995). Prevalence of infection with HIV among the seriously mentally ill: Review of the research and implications for practice. Professional Psychology: Research and Practice, 26, 262–268.CrossRefGoogle Scholar
  15. Cassel, C. (1985). Research in nursing homes: Ethical issues. Journal of the American Geriatrics Society, 33, 795–799.PubMedGoogle Scholar
  16. Cassel, C. (1988). Ethical issues in the conduct of research in long term care. Gerontologist, 28, 90–96.PubMedGoogle Scholar
  17. Centers for Disease Control and Prevention. (2006). Basic statistics. Available at exposure. Last accessed April 3, 2006.Google Scholar
  18. Cournos, F. & McKinnon, K. (1997). HIV seroprevalence among people with severe mental illness in the United States: A critical review. Clinical Psychology Review, 17, 259–269.PubMedCrossRefGoogle Scholar
  19. Cox, S.E. (2005). Interjurisdictional recognition of civil unions, domestic partnerships, and benefits: article: red states, blue states, marriage debates. Ave Maria Law Review, 3, 637–656.Google Scholar
  20. Douaihy, A.B., Stowell, K.R., Bui, T., Daley, D., & Salloum, I. (2005). HIV/AIDS and home-lessness: Part 1: Background and barriers to care. The AIDS Reader, 15(10), 516–520.PubMedGoogle Scholar
  21. Dresser, R. (2001). Dementia research: Ethics and policy for the twenty-first century. Georgia Law Review, 35, 661–690.PubMedGoogle Scholar
  22. Ensign, J. (2003). Ethical issues in qualitative health research with homeless youths. Journal of Advanced Nursing, 43(1), 43–50.PubMedCrossRefGoogle Scholar
  23. Faden, R. & Beauchamp, T. (1986). A History and Theory of Informed Consent. New York: Oxford University Press.Google Scholar
  24. Flanery, M., Gravdal, J., Hendrix., P. et al. (1978). Just sign here...South Dakota Journal of Medicine, 31(5), 33–37.PubMedGoogle Scholar
  25. Flynn, L.M. (1997). Statement. Issues Concerning Informed Consent and Protections of Human Subjects in Research: Hearings before the Subcommittee on Human resources of the House Committee on Government Reform and Oversight, 105th Cong.Google Scholar
  26. Fuller, M. & Sajatovic, M. (2005). Drug Information Handbook for Psychiatry. 5th ed. Cleveland, Ohio: Lexi-Comp., Inc.Google Scholar
  27. Garnett, R.W. (1996). Why informed consent? Human experimentation and the ethics of autonomy. Catholic Lawyer, 36, 455–511.Google Scholar
  28. Gray, B. (1975). Human Subjects in Medical Experimentation: A Sociological Study of the Conduct and Regulation of Clinical Research. New York: Wiley.Google Scholar
  29. Grisso, T. & Appelbaum, P. (1998). Assessing Competence to Consent to Treatment: A Guide for Physicians and Other Health Professionals. New York: Oxford University Press.Google Scholar
  30. Harvey, P., Gow, P. (1994). Introduction. In P. Harvey, P. Gow (Eds.). Sex and Violence: Issues in Representation and Experience (pp. 1–17). New York: Routledge.Google Scholar
  31. Hassar, M. & Weintraub, M. (1976). “Uninformed” consent and the wealthy volunteer: An analysis of patient volunteers in a clinical trial of a new anti-inflammatory drug. Clinical Pharmacology & Therapeutics, 20, 379–386.Google Scholar
  32. Henderly, D.E. & Jampol, L.M. (1991). Diagnosis and treatment of cytomegalovirus retinitis. Journal of Acquired Immune Deficiency Syndromes, 4(1), S6-S10.PubMedGoogle Scholar
  33. High, D.M., Whitehouse, P.J., Post, S.G., & Berg, L. (1994). Guidelines for addressing ethical and legal issues in Alzheimer disease research: A position statement. Alzheimer’s Disease & Associated Disorders, 8 (Supp. 4), 66–74.Google Scholar
  34. Howard, J.M., DeMets, D., & The BHAT Research Group. (1981). How informed is informed consent? Controlled Clinical Trials, 2, 287–303.Google Scholar
  35. Isaac, R.J., Armat, V.C. (1990). Madness in the Streets: How Psychiatry and the Law Abandoned the Mentally Ill. New York: Free Press.Google Scholar
  36. Kaimowitz v. Michigan Department of Mental Health. (1973). U.S. Law Week, 42, 2063 (Circuit Court, Wayne County, Michigan).Google Scholar
  37. Kalichman, S.C., Carey, M.P., & Carey, K.B. (1996). Human immunodeficiency virus (HIV) risk among the seriously mentally ill. Clinical Psychology: Science and Practice, 3, 130–143.CrossRefGoogle Scholar
  38. Kalichman, S.C., Kelly, J.A., Johnson, J.R., & Bulto, M. (1994). Factors associated with risk for HIV infection among chronic mentally ill adults. American Journal of Psychiatry, 151(2), 221–227.PubMedGoogle Scholar
  39. Kapp, M. (1998). Decisional capacity, older human research subjects, and IRBs: Beyond forms and guidelines. Stanford Law & Policy Review, 9, 359–365.Google Scholar
  40. Kennedy, G.J. (2000). Geriatric Mental Health Care: A Treatment Guide for Health Professionals. New York: Guilford Press.Google Scholar
  41. Keyserlingk, E.W., Glass, K., Kogan, S., & Gauthier, S. (1995). Proposed guidelines for the participation of persons with dementia as research subjects. Perspectives in Biology & Medicine, 38, 319–361.Google Scholar
  42. Krotoszynski, R.J. Jr. & E. Gary Spitko, E.G. (2005). Navigating dangerous constitutional straits: A prolegomenon on the federal marriage amendment and the disenfranchise-ment of sexual minorities. University of Colorado Law Review, 76, 599–652.Google Scholar
  43. LeBlang, T.R. & Kirchner, J.L. (1996). Informed consent and Alzheimer disease research: Institutional review board policies and practices. In R. Becker & E. Giacobini (Eds.), Alzheimer’s Disease from Molecular Biology to Therapy (pp. 529–534). Boston: Birkhauser.Google Scholar
  44. Levine, R. J. (1988). Ethics and Regulation of Clinical Research. New Haven, Connecticut: Yale University Press.Google Scholar
  45. Loue, S. (2001). Elder abuse and neglect in medicine and law: The need for reform. Journal of Legal Medicine, 22, 159–209.PubMedCrossRefGoogle Scholar
  46. Lubasch, A.H. (1982). Trial ruled in 1953 death case. N.Y. Times, Sept. 14, A-14.Google Scholar
  47. McArthur, J.C. (2004). HIV dementia: An evolving disease. Journal of Neuroimmunology, 157, 3–10.PubMedCrossRefGoogle Scholar
  48. McCollum, A.T. & Schwartz, A.H. (1969). Pediatric research hospitalization: Its meaning to parents. Pediatric Research, 3, 199–204.PubMedCrossRefGoogle Scholar
  49. McKinnon K, Cournos F, & Herman R. (2002). HIV among people with chronic mental illness. The Psychiatric Quarterly, 73, 17–31.PubMedCrossRefGoogle Scholar
  50. Meisel, A., Roth, L.H., & Lidz, C.W. (1977). Toward a model of the legal doctrine of informed consent. American Journal of Psychiatry, 134, 285–289.PubMedGoogle Scholar
  51. Morrow, G., Gootnick, J., & Schmale, A. (1978). A simple technique for increasing cancer patients’ knowledge of informed consent to treatment. Cancer, 42, 793–799.PubMedCrossRefGoogle Scholar
  52. National Bioethics Advisory Commission. (1998). Research Involving Persons with Mental Disorders That May Affect Decisionmaking Capacity. Rockville, Maryland: National Bioethics Advisory Commission.Google Scholar
  53. Park, L.C., Slaughter, R.S., Covi, L., & Kniffin, H.G., Jr. (1966). The subjective experi-ence of the research patient: An investigation of psychiatric outpatients’ reactions to the research treatment situation. Journal of Nervous & Mental Disease, 143, 199–206.CrossRefGoogle Scholar
  54. Riecken, H.W., & Ravich, R. (1982). Informed consent to biomedical research in Veterans Administration hospitals. Journal of the American Medical Association, 248(3), 344–348.PubMedCrossRefGoogle Scholar
  55. Romero-Daza, N., Weeks, M., & Singer, M. (2003). “Nobody gives a damn if I live or die”: Violence, drugs, and street-level prostitution in inner-city Hartford, Connecticut. Medical Anthropology, 22, 233–259.PubMedCrossRefGoogle Scholar
  56. Rosenberg, P.S. (1995). Scope of the AIDS epidemic in the United States. Science, 270, 1372–1375.PubMedCrossRefGoogle Scholar
  57. Roth, L.H., Lidz, C.W., Meisel, A., Soloff, P.H., Kaufman, K., Spiker, D.G., et al. (1982). Competency to decide about treatment or research: An overview of some empirical data. International Journal of Law and Psychiatry, 5, 29–50.CrossRefGoogle Scholar
  58. Rothman, D.J. (1991). Strangers at the Bedside: A History of How Law and Bioethics Transformed Medical Decision Making. New York: Basic Books.Google Scholar
  59. Sachs, G. & Cassel, C. (1989). Ethical aspects of dementia. Neurologic Clinics, 7, 845–858.PubMedGoogle Scholar
  60. Sacks, M.H., Perry, S., Graver, R., Shindledecker, R., & Hall, S. (1990). Self-reported HIV-related risk behaviors in acute psychiatric inpatients. Hospital & Community Psychiatry, 41, 1253–1255.Google Scholar
  61. Scott v. Casey. (1983). 562 F. Supp. 475 (N.D. Ga.).Google Scholar
  62. Susser, E., Valencia, E., & Conover, S. (1993). Prevalence of HIV infection among psychi-atric patients in a New York City men’s shelter. American Journal of Public Health, 83, 568–570.PubMedCrossRefGoogle Scholar
  63. Universal Declaration of Human Rights. (1948). G.A. Res. 217A (III), U.N. Doc. A/810 at 71.Google Scholar
  64. Valenti v. Prudden. (1977). 58 A.D.2d 956, 397 N.Y.S.2d 181.Google Scholar
  65. Williams, R.L., Rieckmann, K.H., Trenholme, G.M., Frischer, H., & Carson, P.E. (1977). The use of a test to determine that consent is informed. Military Medicine, 142, 542–545.PubMedGoogle Scholar
  66. Wolf, L.E. & Lo, B. (2004). Informed consent in HIV research. FOCUS, 19(4), 5–6.PubMedGoogle Scholar
  67. Young, D.A., Zakzanis, K.K., Bailey, C., Davila, R., Griese, J., & Sartory, T.A. (1998). Further parameters of insight and neuropsychological deficit in schizophrenia and other chronic mental disease. Journal of Nervous and Mental Disease, 186(1), 44–50.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Sana Loue
    • 1
  • Earl C. Pike
    • 2
  1. 1.Case Western Reserve UniversityCleveland
  2. 2.AIDS Taskforce of Greater ClevelandCleveland

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