The Semantics of Stereotactic Radiation Therapy

  • Louis Potters


Radiation therapy, or the therapeutic use of radiation for the treatment of malignant and benign disease, continues to evolve from the days when radium was first discovered by the Curies through to modern linear accelerators with multileaf collimation and conformal treatment planning. The basic tenets of radiation therapy have remained identical over the past 100-plus years, namely to improve the therapeutic index by enhancing tumor cell death while preserving normal tissue.


Radiat Oncol Biol Phys Stereotactic Radiosurgery Stereotactic Radiation Multileaf Collimation Radiation Delivery 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Douglas RM, Beatty J, Gall K, et al. Dosimetric results from a feasibility study of a novel radiosurgical source for irradiation of intracranial metastases. Int J Radiat Oncol Biol Phys 1996; 36:443–450.PubMedGoogle Scholar
  2. 2.
    Adams EJ, Cosgrove VP, Shepherd SF, et al. Comparison of a multi-leaf collimator with conformal blocks for the delivery of stereotactically guided conformal radiotherapy. Radiother Oncol 1999; 51:205–209.CrossRefPubMedGoogle Scholar
  3. 3.
    Rosenthal DI, Glatstein E. We’ve got a treatment, but what’s the disease? Or a brief history of hypofractionation and its relationship to stereotactic radiosurgery. Oncologist 1996; 1:1–7.PubMedGoogle Scholar
  4. 4.
    Shepherd SF, Childs PJ, Graham JD, et al. Whole body doses from linear accelerator-based stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 1997; 38:657–665.PubMedGoogle Scholar
  5. 5.
    Timmerman R, Papiez L, McGarry R, et al. Extracranial stereotactic radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer. Chest 2003; 124:1946–1955.CrossRefPubMedGoogle Scholar
  6. 6.
    Kim KH, Cho MJ, Kim JS, et al. Isocenter accuracy in frameless stereotactic radiotherapy using implanted fiducials. Int J Radiat Oncol Biol Phys 2003; 56:266–273.CrossRefPubMedGoogle Scholar
  7. 7.
    Sperduto PW. A review of stereotactic radiosurgery in the management of brain metastases. Technol Cancer Res Treat 2003; 2:105–110.PubMedGoogle Scholar
  8. 8.
    Phillips MH, Stelzer KJ, Griffin TW, et al. Stereotactic radiosurgery: a review and comparison of methods. J Clin Oncol 1994; 12:1085–1099.PubMedGoogle Scholar
  9. 9.
    Brown PD, Wald JT, McDermott MW, et al. Oncodiagnosis panel: 2002. Metastatic NSCLC. Radiographics 2003; 23:1591–1611.CrossRefGoogle Scholar
  10. 10.
    Wulf J, Haedinger U, Oppitz U, et al. Stereotactic radiotherapy for primary lung cancer and pulmonary metastases: a noninvasive treatment approach in medically inoperable patients. Int J Radiat Oncol Biol Phys 2004; 60:186–196.CrossRefPubMedGoogle Scholar
  11. 11.
    Fuss M, Thomas CR Jr. Stereotactic body radiation therapy: an ablative treatment option for primary and secondary liver tumors. Ann Surg Oncol 2004; 11:130–138.CrossRefPubMedGoogle Scholar
  12. 12.
    Fuss M, Salter BJ, Cavanaugh SX, et al. Daily ultrasound-based image-guided targeting for radiotherapy of upper abdominal malignancies. Int J Radiat Oncol Biol Phys 2004; 59:1245–1256.CrossRefPubMedGoogle Scholar
  13. 13.
    Larson DA, Bova F, Eisert D, et al. Current radiosurgery practice: results of an ASTRO survey. Task Force on Stereotactic Radiosurgery, American Society for Therapeutic Radiology and Oncology. Int J Radiat Oncol Biol Phys 1994; 28:523–526.PubMedGoogle Scholar
  14. 14.
    Kondziolka D, Lunsford LD, Loeffler JS, et al. Radiosurgery and radiotherapy: observations and clarifications. J Neurosurg 2004; 101:585–589.CrossRefPubMedGoogle Scholar
  15. 15.
    Department of Health and Human Services, Centers for Medicare & Medicaid Services, 42 CFR Part 419 [CMS-1427-FC]. Available at (p. 103).Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Louis Potters
    • 1
  1. 1.South Nassau Communities HospitalOceansideUSA

Personalised recommendations