Pituitary and Pituitary Region Tumors: Medical Therapy Perspective

  • Mansur E. Shomali


The management of tumors in or around the pituitary region requires specialized attention to both issues of mass effect on the adjacent critical structures and to the diagnosis and management of endocrine dysfunction. Careful assessment of endocrine function is necessary before therapy for a number of reasons. First, the nature of the pituitary lesion needs to be determined. Tumors of pituitary origin have the potential to respond to medical therapy. In fact, medical therapy is preferred as a primary therapy over surgery and radiation for some tumor subtypes such as prolactinomas. Tumors not of pituitary origin do not respond to medical therapy and should be treated with the other modalities. Second, syndromes of pituitary hormone excess may occur and may be an important factor in the choice of therapy. Third, these patients need to be treated for the hypopituitarism that may occur as a result of the mass lesion or of the treatments thereof.


Pituitary Adenoma Pituitary Tumor Stereotactic Radiosurgery Tumor Shrinkage Cushing Syndrome 
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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Mansur E. Shomali
    • 1
  1. 1.Division of Endocrinology, Union Memorial HospitalUniversity of Maryland School of MedicineBaltimoreUSA

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