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Abstract

Pituitary adenomas are tumors that make up a significant portion of neurosurgical practice. According to the Japanese Brain Tumor Registry [1], pituitary adenomas (n = 6653) comprise 17.4% of all primary brain tumors (N = 38,273). Their clinical presentation can be divided into two groups: functioning adenomas that secrete excess pituitary hormones resulting in endocrinologic symptoms and signs, and nonfunctioning adenomas that do not secrete biologically active hormones. All adenomas, particularly when they grow and extend outside the sella turcica, will cause neurologic deficit due to compression of surrounding tissues (e.g., bitemporal hemianopsia and hypopituitarism).

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Takakura, K., Hayashi, M., Izawa, M. (2008). Pituitary Tumors. In: Chin, L.S., Regine, W.F. (eds) Principles and Practice of Stereotactic Radiosurgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-71070-9_26

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