Neuroimaging in Radiosurgery Treatment Planning and Follow-up Evaluation

  • Clark C. Chen
  • Paul H. Chapman
  • Hanne Kooy
  • Jay S. Loeffler


Radiosurgery refers to the precise delivery of a large, single dose of radiation to a focal target. The focal dose distribution allows for a positive therapeutic gain. Because of the opacity of the cranial vault, target volume definition relies entirely on the anatomic accuracy of the available imaging modalities. The need for accurate anatomic visualization is magnified by the use of higher radiation dose delivered in radiosurgery as compared with radiotherapy. To achieve maximal spatial accuracy in radiosurgical planning, an understanding of the basic principles underlying neuroimaging as well as the limitations associated with each imaging modality is mandatory. Additionally, the optimal management of patients after radiosurgery requires knowledge of the expected neuroimaging changes as they relate to clinical outcome. These issues will be reviewed in this chapter.


Malignant Glioma Radiat Oncol Biol Phys Arteriovenous Malformation Trigeminal Neuralgia Cerebral Blood Volume 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Clark C. Chen
    • 1
  • Paul H. Chapman
    • 1
  • Hanne Kooy
    • 2
  • Jay S. Loeffler
    • 2
  1. 1.Radiosurgery, Department of NeurosurgeryMassachusetts General HospitalBostonUSA
  2. 2.Department of Radiation OncologyMassachusetts General HospitalBostonUSA

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