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Meningioma

  • Carlos A. Mattozo
  • Antonio A. F. de Salles

Abstract

Meningiomas are generally benign lesions that account for 15% to 20% of primary brain tumors, affect predominately middle-aged patients, and occur predominately in females [1], [2]. The atypical and malignant meningiomas are characterized by successive recurrences and an aggressive behavior. Among all meningiomas, their incidence varies in the literature ranging from 4.7% to 7.1% and 1.0% to 3.7% for atypical and malignant, respectively [3]–[6]. There is absence of female predominance in malignant meningiomas suggesting that endocrinologic influences apparently correlated with the genesis of benign meningiomas are not active in malignant ones [4].

Keywords

Skull Base Radiat Oncol Biol Phys Cavernous Sinus Gamma Knife Stereotactic Radiosurgery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bondy M, Ligon BL. Epidemiology and etiology of intracranial meningiomas: a review. J Neurooncol 1996;29:197–205.PubMedGoogle Scholar
  2. 2.
    Rohringer M, Sutherland GR, Louw DF, et al. Incidence and clinicopathological features of meningioma. J Neurosurg 1989;71:665–672.PubMedGoogle Scholar
  3. 3.
    Jaaskelainen J, Haltia M, Servo A. Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy, and outcome. Surg Neurol 1986;25:233–242.PubMedGoogle Scholar
  4. 4.
    Mahmood A, Caccamo DV, Tomecek FJ, et al. Atypical and malignant meningiomas: a clinicopathological review. Neurosurgery 1993;33:955–963.PubMedGoogle Scholar
  5. 5.
    Palma L, Celli P, Franco C, et al. Long-term prognosis for atypical and malignant meningiomas: a study of 71 surgical cases. J Neurosurg 1997;86:793–800.PubMedGoogle Scholar
  6. 6.
    Perry A, Scheithauer BW, Stafford SL, et al. “Malignancy“ in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 1999;85:2046–2056.PubMedGoogle Scholar
  7. 7.
    Drummond KJ, Zhu JJ, Black PM. Meningiomas: updating basic science, management, and outcome. Neurologist 2004;10:113–130.PubMedGoogle Scholar
  8. 8.
    Kleihues P, Louis DN, Scheithauer BW, et al. The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 2002;61:215–225;discussion 226–219.PubMedGoogle Scholar
  9. 9.
    Hug EB, Devries A, Thornton AF, et al. Management of atypical and malignant meningiomas: role of high-dose, 3D-conformal radiation therapy. J Neurooncol 2000;48:151–160.PubMedGoogle Scholar
  10. 10.
    Pourel N, Auque J, Bracard S, et al. Efficacy of external fractionated radiation therapy in the treatment of meningiomas: a 20-year experience. Radiother Oncol 2001;61:65–70.PubMedGoogle Scholar
  11. 11.
    Ikeda H, Yoshimoto T. Immunohistochemical study of anaplastic meningioma with special reference to the phenotypic change of intermediate filament protein. Ann Diagn Pathol 2003;7:214–222.PubMedGoogle Scholar
  12. 12.
    al-Mefty O, Kadri PA, Pravdenkova S, et al. Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings. J Neurosurg 2004;101:210–218.PubMedGoogle Scholar
  13. 13.
    Simpson D. The recurrence of intracranial meningiomas after surgical treatment. J Neurochem 1957;20:22–39.Google Scholar
  14. 14.
    Adegbite AB, Khan MI, Paine KW, et al. The recurrence of intracranial meningiomas after surgical treatment. J Neurosurg 1983;58:51–56.PubMedGoogle Scholar
  15. 15.
    Marks LB, Spencer DP. The influence of volume on the tolerance of the brain to radiosurgery. J Neurosurg 1991;75:177–180.PubMedGoogle Scholar
  16. 16.
    Mirimanoff RO, Dosoretz DE, Linggood RM, et al. Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 1985;62:18–24.PubMedGoogle Scholar
  17. 17.
    Sekhar LN, Patel S, Cusimano M, et al. Surgical treatment of meningiomas involving the cavernous sinus: evolving ideas based on a ten year experience. Acta Neurochir Suppl 1996;65:58–62.PubMedGoogle Scholar
  18. 18.
    Sen C, Hague K. Meningiomas involving the cavernous sinus: histological factors affecting the degree of resection. J Neurosurg 1997;87:535–543.PubMedGoogle Scholar
  19. 19.
    Sindou MP, Alaywan M. Most intracranial meningiomas are not cleavable tumors: anatomic-surgical evidence and angiographic predictibility. Neurosurgery 1998;42:476–480.PubMedGoogle Scholar
  20. 20.
    al-Mefty O, Ayoubi S, Smith RR. The petrosal approach: indications, technique, and results. Acta Neurochir Suppl (Wien) 1991;53:166–170.Google Scholar
  21. 21.
    Bricolo AP, Turazzi S, Talacchi A, et al. Microsurgical removal of petroclival meningiomas: a report of 33 patients. Neurosurgery 1992;31:813–828;discussion 828.PubMedGoogle Scholar
  22. 22.
    Couldwell WT, Fukushima T, Giannotta SL, et al. Petroclival meningiomas: surgical experience in 109 cases. J Neurosurg 1996;84:20–28.PubMedGoogle Scholar
  23. 23.
    DeMonte F, Smith HK, al-Mefty O. Outcome of aggressive removal of cavernous sinus meningiomas. J Neurosurg 1994;81:245–251.PubMedGoogle Scholar
  24. 24.
    O’Sullivan MG, van Loveren HR, Tew JM Jr. The surgical resectability of meningiomas of the cavernous sinus. Neurosurgery 1997;40:238–244;discussion 245–237.PubMedGoogle Scholar
  25. 25.
    Sekhar LN, Swamy NK, Jaiswal V, et al. Surgical excision of meningiomas involving the clivus: preoperative and intraoperative features as predictors of postoperative functional deterioration. 1994;J Neurosurg 81:860–868.Google Scholar
  26. 26.
    De Jesus O, Sekhar LN, Parikh HK, et al. Long-term follow-up of patients with meningiomas involving the cavernous sinus: recurrence, progression, and quality of life. Neurosurgery 1996;39:915–919;discussion 919–920.PubMedGoogle Scholar
  27. 27.
    Little KM, Friedman AH, Sampson JH, et al. Surgical management of petroclival meningiomas: defining resection goals based on risk of neurological morbidity and tumor recurrence rates in 137 patients. Neurosurgery 2005; 56:546–559; discussion 546–559.PubMedGoogle Scholar
  28. 28.
    Nanda A, Jawahar A, Sathyanarayana S. Microsurgery for potential radiosurgical skull base lesions: a retrospective analysis and comparison of results. Skull Base 2003;13:131–138.PubMedGoogle Scholar
  29. 29.
    Soyuer S, Chang EL, Selek U, et al. Radiotherapy after surgery for benign cerebral meningioma. Radiother Oncol 2004;71:85–90.PubMedGoogle Scholar
  30. 30.
    Taylor BW Jr, Marcus RB Jr, Friedman WA, et al. The meningioma controversy: postoperative radiation therapy. Int J Radiat Oncol Biol Phys 1988;15:299–304.PubMedGoogle Scholar
  31. 31.
    Barbaro NM, Gutin PH, Wilson CB, et al. Radiation therapy in the treatment of partially resected meningiomas. Neurosurgery 1987;20:525–528.PubMedGoogle Scholar
  32. 32.
    Glaholm J, Bloom HJ, Crow JH. The role of radiotherapy in the management of intracranial meningiomas: the Royal Marsden Hospital experience with 186 patients. Int J Radiat Oncol Biol Phys 1990;18:755–761.PubMedGoogle Scholar
  33. 33.
    Goldsmith BJ, Wara WM, Wilson CB, et al. Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 1994;80:195–201.PubMedGoogle Scholar
  34. 34.
    Wilson CB. Cavernous sinus meningiomas. Surg Neurol 1996;46:191–192.PubMedGoogle Scholar
  35. 35.
    Nutting C, Brada M, Brazil L, et al. Radiotherapy in the treatment of benign meningioma of the skull base. J Neurosurg 1999;90:823–827.PubMedGoogle Scholar
  36. 36.
    Milosevic MF, Frost PJ, Laperriere NJ, et al. Radiotherapy for atypical or malignant intracranial meningioma. Int J Radiat Oncol Biol Phys 1996;34:817–822.PubMedGoogle Scholar
  37. 37.
    Dziuk TW, Woo S, Butler EB, et al. Malignant meningioma: an indication for initial aggressive surgery and adjuvant radiotherapy. J Neurooncol 1998;37:177–188.PubMedGoogle Scholar
  38. 38.
    Ware ML, Larson DA, Sneed PK, et al. Surgical resection and permanent brachytherapy for recurrent atypical and malignant meningioma. Neurosurgery 2004;54:55–63;discussion 63–54.PubMedGoogle Scholar
  39. 39.
    al-Mefty O, Kersh JE, Routh A, et al. The long-term side effects of radiation therapy for benign brain tumors in adults. J Neurosurg 1990;73:502–512.PubMedGoogle Scholar
  40. 40.
    Crossen JR, Garwood D, Glatstein E, et al. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiationinduced encephalopathy. J Clin Oncol 1994;12:627–642.PubMedGoogle Scholar
  41. 41.
    Torres RC, Frighetto L, De Salles AA, et al. Radiosurgery and stereotactic radiotherapy for intracranial meningiomas. Neurosurg Focus 2003;14:e5.PubMedGoogle Scholar
  42. 42.
    Torres RC, De Salles AA, Frighetto L, et al. Long-term follow-up using linac radiosurgery and stereotactic radiotherapy as a minimally invasive treatment for intracranial meningiomas. Radiosurgery 2004;5:115–123.Google Scholar
  43. 43.
    De Salles AA, Frighetto L, Grande CV, et al. Radiosurgery and stereotactic radiation therapy of skull base meningiomas: proposal of a grading system. Stereotact Funct Neurosurg 2001;76:218–229.PubMedGoogle Scholar
  44. 44.
    Selch MT, Ahn E, Laskari A, et al. Stereotactic radiotherapy for treatment of cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys 2004;59:101–111.PubMedGoogle Scholar
  45. 45.
    Kondziolka D, Lunsford LD. Radiosurgery of meningiomas. Neurosurg Clin N Am 1992;3:219–230.PubMedGoogle Scholar
  46. 46.
    Hakim R, Alexander E 3rd, Loeffler JS, et al. Results of linear accelerator-based radiosurgery for intracranial meningiomas. Neurosurgery 1998;42:446–453;discussion 453–444.PubMedGoogle Scholar
  47. 47.
    Shafron DH, Friedman WA, Buatti JM, et al. Linac radiosurgery for benign meningiomas. Int J Radiat Oncol Biol Phys 1999;43:321–327.PubMedGoogle Scholar
  48. 48.
    Spiegelmann R, Nissim O, Menhel J, et al. Linear accelerator radiosurgery for meningiomas in and around the cavernous sinus. Neurosurgery 2002;51:1373–1379;discussion 1379–1380.PubMedGoogle Scholar
  49. 49.
    Iwai Y, Yamanaka K, Ishiguro T. Gamma knife radiosurgery for the treatment of cavernous sinus meningiomas. Neurosurgery 52003;2:517–524;discussion 523–514.Google Scholar
  50. 50.
    Kobayashi T, Kida Y, Mori Y. Long-term results of stereotactic gamma radiosurgery of meningiomas. Surg Neurol 2001;55:325–331.PubMedGoogle Scholar
  51. 51.
    Kondziolka D, Levy EI, Niranjan A, et al. Long-term outcomes after meningioma radiosurgery: physician and patient perspectives. J Neurosurg 1999;91:44–50.PubMedGoogle Scholar
  52. 52.
    Kondziolka D, Nathoo N, Flickinger JC, et al. Long-term results after radiosurgery for benign intracranial tumors. Neurosurgery 2003;53:815–821; discussion 821–812.PubMedGoogle Scholar
  53. 53.
    Leksell L. Stereotactic radiosurgery. J Neurol Neurosurg Psychiatry 1983;46:797–803.PubMedGoogle Scholar
  54. 54.
    Stafford SL, Pollock BE, Foote RL, et al. Meningioma radiosurgery: tumor control, outcomes, and complications among 190 consecutive patients. Neurosurgery 2001;49:1029–1037;discussion 1037–1028.PubMedGoogle Scholar
  55. 55.
    Vernimmen FJ, Harris JK, Wilson JA, et al. Stereotactic proton beam therapy of skull base meningiomas. Int J Radiat Oncol Biol Phys 2001;49:99–105.PubMedGoogle Scholar
  56. 56.
    Nicolato A, Foroni R, Alessandrini F, et al. The role of Gamma Knife radiosurgery in the management of cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys 2002;53:992–1000.PubMedGoogle Scholar
  57. 57.
    Subach BR, Lunsford LD, Kondziolka D, et al. Management of petroclival meningiomas by stereotactic radiosurgery. Neurosurgery 1998;42:437–443;discussion 443–435.PubMedGoogle Scholar
  58. 58.
    Pendl G, Schrottner O, Eustacchio S, et al. Stereotactic radiosurgery of skull base meningiomas. Minim Invasive Neurosurg 1997;40:87–90.PubMedGoogle Scholar
  59. 59.
    Liscak R, Simonova G, Vymazal J, et al. Gamma knife radiosurgery of meningiomas in the cavernous sinus region. Acta Neurochir (Wien) 1999;141:473–480.Google Scholar
  60. 60.
    Nedzi LA, Kooy H, Alexander E 3rd, et al. Variables associated with the development of complications from radiosurgery of intracranial tumors. Int J Radiat Oncol Biol Phys 1991;21:591–599.PubMedGoogle Scholar
  61. 61.
    Chang JH, Chang JW, Choi JY, et al. Complications after gamma knife radiosurgery for benign meningiomas. J Neurol Neurosurg Psychiatry 2003;74:226–230.PubMedGoogle Scholar
  62. 62.
    Valentino V, Schinaia G, Raimondi AJ. The results of radiosurgical management of 72 middle fossa meningiomas. Acta Neurochir (Wien) 1993;122:60–70.Google Scholar
  63. 63.
    DiBiase SJ, Kwok Y, Yovino S, et al. Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas. Int J Radiat Oncol Biol Phys 2004;60:1515–1519.PubMedGoogle Scholar
  64. 64.
    Pollock BE, Stafford SL, Utter A, et al. Stereotactic radiosurgery provides equivalent tumor control to Simpson grade 1 resection for patients with small-to medium-size meningiomas. Int J Radiat Oncol Biol Phys 2003;55:1000–1005.PubMedGoogle Scholar
  65. 65.
    Flickinger JC, Kondziolka D, Maitz AH, et al. Gamma knife radiosurgery of imaging-diagnosed intracranial meningioma. Int J Radiat Oncol Biol Phys 2003;56:801–806.PubMedGoogle Scholar
  66. 66.
    Nakatomi H, Sasaki T, Kawamoto S, et al. Primary cavernous sinus malignant lymphoma treated by gamma knife radiosurgery: case report and review of the literature. Surg Neurol 1996;46:272–278;discussion 278–279.PubMedGoogle Scholar
  67. 67.
    Kim DG, Kim Ch H, Chung HT, et al. Gamma Knife surgery of superficially located meningioma. J Neurosurg 2005;102(Suppl):255–258.PubMedGoogle Scholar
  68. 68.
    Kotapka MJ, Kalia KK, Martinez AJ, et al. Infiltration of the carotid artery by cavernous sinus meningioma. J Neurosurg 1994;81:252–255.PubMedGoogle Scholar
  69. 69.
    Larson JJ, van Loveren HR, Balko MG, et al. Evidence of meningioma infiltration into cranial nerves: clinical implications for cavernous sinus meningiomas. J Neurosurg 1995;83:596–599.PubMedGoogle Scholar
  70. 70.
    Zentner J, Meyer B, Vieweg U, et al. Petroclival meningiomas: is radical resection always the best option? J Neurol Neurosurg Psychiatry 1997;62:341–345.PubMedGoogle Scholar
  71. 71.
    Liscak R, Kollova A, Vladyka V, et al. Gamma Knife radiosurgery of skull base meningiomas. Acta Neurochir Suppl 2004;91:65–74.PubMedGoogle Scholar
  72. 72.
    Chuang CC, Chang CN, Tsang NM, et al. Linear accelerator-based radiosurgery in the management of skull base meningiomas. J Neurooncol 2004;66:241–249.PubMedGoogle Scholar
  73. 73.
    Roche PH, Pellet W, Fuentes S, et al. Gamma Knife radiosurgical management of petroclival meningiomas results and indications. Acta Neurochir (Wien) 2003;145:883–888;discussion 888.Google Scholar
  74. 74.
    Tishler RB, Loeffler JS, Lunsford LD, et al. Tolerance of cranial nerves of the cavernous sinus to radiosurgery. Int J Radiat Oncol Biol Phys 1993;27:215–221.PubMedGoogle Scholar
  75. 75.
    Leber KA, Bergloff J, Pendl G. Dose-response tolerance of the visual pathways and cranial nerves of the cavernous sinus to stereotactic radiosurgery. J Neurosurg 1998;88:43–50.PubMedGoogle Scholar
  76. 76.
    Stafford SL, Pollock BE, Leavitt JA, et al. A study on the radiation tolerance of the optic nerves and chiasm after stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 2003;55:1177–1181.PubMedGoogle Scholar
  77. 77.
    Chen JC, Giannotta SL, Yu C, et al. Radiosurgical management of benign cavernous sinus tumors: dose profiles and acute complications. Neurosurgery 2001;48:1022–1030;discussion 1030–1022.PubMedGoogle Scholar
  78. 78.
    De Salles AA, Bajada CL, Goetsch S, et al. Radiosurgery of cavernous sinus tumors. Acta Neurochir Suppl (Wien) 1993;58:101–103.Google Scholar
  79. 79.
    Lee JY, Niranjan A, McInerney J, et al. Stereotactic radiosurgery providing long-term tumor control of cavernous sinus meningiomas. J Neurosurg 2002;97:65–72.PubMedGoogle Scholar
  80. 80.
    Tome WA, Mehta MP, Meeks SL, et al. Fractionated stereotactic radiotherapy: a short review. Technol Cancer Res Treat 2002;1:153–172.PubMedGoogle Scholar
  81. 81.
    Gill SS, Thomas DG, Warrington AP, et al. Relocatable frame for stereotactic external beam radiotherapy. Int J Radiat Oncol Biol Phys 1991;20:599–603.PubMedGoogle Scholar
  82. 82.
    Alheit H, Dornfeld S, Dawel M, et al. Patient position reproducibility in fractionated stereotactically guided conformal radiotherapy using the BrainLab mask system. Strahlenther Onkol 2001;177:264–268.PubMedGoogle Scholar
  83. 83.
    Kooy HM, Dunbar SF, Tarbell NJ, et al. Adaptation and verification of the relocatable Gill-Thomas-Cosman frame in stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 1994;30:685–691.PubMedGoogle Scholar
  84. 84.
    Solberg T, Ford J, Medin P, et al. Reproducibility of frame positioning for fractionated stereotactic radiosurgery. J Radiosurg 1999;2:57–64.Google Scholar
  85. 85.
    Lo SS, Cho KH, Hall WA, et al. Single dose versus fractionated stereotactic radiotherapy for meningiomas. Can J Neurol Sci 2002;29:240–248.PubMedGoogle Scholar
  86. 86.
    Milker-Zabel S, Zabel A, Schulz-Ertner D, et al. Fractionated stereotactic radiotherapy in patients with benign or atypical intracranial meningioma: long-term experience and prognostic factors. Int J Radiat Oncol Biol Phys 2005;61:809–816.PubMedGoogle Scholar
  87. 87.
    Debus J, Wuendrich M, Pirzkall A, et al. High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: long-term results. J Clin Oncol 2001;19:3547–3553.PubMedGoogle Scholar
  88. 88.
    Baumert BG, Norton IA, Davis JB. Intensity-modulated stereotactic radiotherapy vs. stereotactic conformal radiotherapy for the treatment of meningioma located predominantly in the skull base. Int J Radiat Oncol Biol Phys 2003;57:580–592.PubMedGoogle Scholar
  89. 89.
    Ernst-Stecken A, Lambrecht U, Ganslandt O, et al. Radiosurgery of small skull-base lesions no advantage for intensity-modulated stereotactic radiosurgery versus conformal arc technique. Strahlenther Onkol 2005;181:336–344.PubMedGoogle Scholar
  90. 90.
    Gabibov GA, Blinkov SM, Tcherekayev VA. The management of optic nerve meningiomas and gliomas. J Neurosurg 1988;68:889–893.PubMedGoogle Scholar
  91. 91.
    Kupersmith MJ, Warren FA, Newall J, et al. Irradiation of meningiomas of the intracranial anterior visual pathway. Ann Neurol 1987;21:131–137.PubMedGoogle Scholar
  92. 92.
    Wara WM, Sheline GE, Newman H, et al. Radiation therapy of meningiomas. Am J Roentgenol Radium Ther Nucl Med 1975;123:453–458.PubMedGoogle Scholar
  93. 93.
    Andrews DW, Faroozan R, Yang BP, et al. Fractionated stereotactic radiotherapy for the treatment of optic nerve sheath meningiomas: preliminary observations of 33 optic nerves in 30 patients with historical comparison to observation with or without prior surgery. Neurosurgery 2002;51:890–902;discussion 903–894.PubMedGoogle Scholar
  94. 94.
    Baumert BG, Villa S, Studer G, et al. Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma. Radiother Oncol 2004;72:169–174.PubMedGoogle Scholar
  95. 95.
    Ojemann SG, Sneed PK, Larson DA, et al. Radiosurgery for malignant meningioma: results in 22 patients. J Neurosurg 2000;93(Suppl 3):62–67.PubMedGoogle Scholar
  96. 96.
    Harris AE, Lee JY, Omalu B, et al. The effect of radiosurgery during management of aggressive meningiomas. Surg Neurol 2003;60:298–305;discussion 305.PubMedGoogle Scholar
  97. 97.
    Huffmann BC, Reinacher PC, Gilsbach JM. Gamma Knife surgery for atypical meningiomas. J Neurosurg 2005;102(Suppl):283–286.PubMedGoogle Scholar
  98. 98.
    Abdel-Aziz KM, Froelich SC, Dagnew E, et al. Large sphenoid wing meningiomas involving the cavernous sinus: conservative surgical strategies for better functional outcomes. Neurosurgery 2004;54:1375–1383;discussion 1383–1374.PubMedGoogle Scholar
  99. 99.
    Maruyama K, Shin M, Kurita H, et al. Proposed treatment strategy for cavernous sinus meningiomas: a prospective study. Neurosurgery 2004;55:1068–1075.PubMedGoogle Scholar
  100. 100.
    Frighetto L, De Salles AA, Behnke E, et al. Image-guided frameless stereotactic biopsy sampling of parasellar lesions. Technical note. J Neurosurg 2003;98:920–925.PubMedGoogle Scholar
  101. 101.
    Duma CM, Lunsford LD, Kondziolka D, et al. Stereotactic radiosurgery of cavernous sinus meningiomas as an addition or alternative to microsurgery. Neurosurgery 1993;32:699–704;discussion 704–695.PubMedGoogle Scholar
  102. 102.
    Suzuki M, Mizoi K, Yoshimoto T. Should meningiomas involving the cavernous sinus be totally resected? Surg Neurol 1995;44:3–10;discussion 10–13.PubMedGoogle Scholar
  103. 103.
    Flickinger JC. An integrated logistic formula for prediction of complications from radiosurgery. Int J Radiat Oncol Biol Phys 1989;17:879–885.PubMedGoogle Scholar
  104. 104.
    Kjellberg RN, Davis KR, Lyons S, et al. Bragg peak proton beam therapy for arteriovenous malformation of the brain. Clin Neurosurg 1983;31:248–290.PubMedGoogle Scholar
  105. 105.
    Yang S, Law M, Zagzag D, et al. Dynamic contrast-enhanced perfusion MR imaging measurements of endothelial permeability: differentiation between atypical and typical meningiomas. AJNR Am J Neuroradiol 2003;24:1554–1559.PubMedGoogle Scholar
  106. 106.
    Kalala JP, Maes L, Vandenbroecke C, et al. The hTERT protein as a marker for malignancy in meningiomas. Oncol Rep 2005;13:273–277.PubMedGoogle Scholar
  107. 107.
    Maes L, Lippens E, Kalala JP, et al. The hTERT-protein and Ki-67 labelling index in recurrent and non-recurrent meningiomas. Cell Prolif 2005;38:3–12.PubMedGoogle Scholar
  108. 108.
    Wrobel G, Roerig P, Kokocinski F, et al. Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression. Int J Cancer 2005;114:249–256.PubMedGoogle Scholar
  109. 109.
    Rohde V, Spangenberg P, Mayfrank L, et al. Advanced neuronavigation in skull base tumors and vascular lesions. Minim Invasive Neurosurg 2005;48:13–18.PubMedGoogle Scholar
  110. 110.
    Kamada K, Todo T, Masutani Y, et al. Combined use of tractography-integrated functional neuronavigation and direct fiber stimulation. J Neurosurg 2005;102:664–672.PubMedGoogle Scholar
  111. 111.
    Cook SW, Smith Z, Kelly DF. Endonasal transsphenoidal removal of tuberculum sellae meningiomas: technical note. Neurosurgery 2004;55:239–244;discussion 244–236.PubMedGoogle Scholar
  112. 112.
    Couldwell WT, Weiss MH, Rabb C, et al. Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in 105 cases. Neurosurgery 2004;55:539–547;discussion 547–550.PubMedGoogle Scholar
  113. 113.
    Jho HD, Alfieri A. Endoscopic glabellar approach to the anterior skull base: a technical note. Minim Invasive Neurosurg 2002;45:185–188.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Carlos A. Mattozo
    • 1
  • Antonio A. F. de Salles
    • 1
  1. 1.Department of Surgery, Division of NeurosurgeryDavid Geffen School of Medicine at UCLALos AngelesUSA

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