CyberKnife Radiosurgery

  • John R. AdlerJr.
  • Alexander Muacevic
  • Pantaleo Romanelli


Conceptually, the lineage of CyberKnife (Accuray Inc., Sunnyvale, CA) technology derives from the clinical principles that underlie stereotactic radiosurgery. This minimally invasive procedure involves the precise delivery of large doses of ionizing radiation to destroy well-defined targets without injuring the surrounding and intervening healthy tissue. This objective is achieved using large numbers of narrow beams that emanate from a wide array of directions and intersect (and therefore accumulate) within the volume selected for ablation. The cumulative dose that can be administered this way overwhelms any capacity for cellular repair, thereby typically ensuring tissue destruction.


Radiat Oncol Biol Phys Trigeminal Neuralgia Gamma Knife Stereotactic Radiosurgery Treatment Beam 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • John R. AdlerJr.
    • 1
  • Alexander Muacevic
    • 2
  • Pantaleo Romanelli
    • 3
    • 4
    • 5
  1. 1.Stanford University Medical CenterStanfordUSA
  2. 2.CyberKnife Center MunichMunichGermany
  3. 3.Department of NeurologyState University of New YorkStony BrookUSA
  4. 4.Department of NeurosurgeryStanford UniversityStanfordUSA
  5. 5.Functional Neurosurgery, Department of NeurosurgeryIRCCS NeuromedPozzilliItaly

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