Consequences of Antimicrobial Chemotherapy: Overgrowth, Resistance, and Virulence

  • Stephanie J. Dancer


The right antibiotic, given at the right time and in the correct dose, can cure infection and save lives. Unfortunately, these drugs cause adverse effects, which sometimes make things worse. These may be due to resistant organisms that overgrow in response to a course of antibiotics, or they may be due to the fact that the original pathogen was not eradicated and continues to cause a problem. It is even possible that the original pathogen actually becomes more virulent following exposure to antibiotics. This article reviews the evidence that getting it wrong regarding antibiotic therapy creates more problems for individual patients as well as encouraging antibiotic resistance for future patients.


Staphylococcus Aureus Antimicrob Agent Antimicrobial Chemotherapy Virulence Determinant Fusidic Acid 
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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Stephanie J. Dancer
    • 1
  1. 1.Department of MicrobiologSouthern General HospitalGlasgowScotland

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