Major Gene Detection

  • Shizhong Xu


When a quantitative trait is controlled by the segregation of a major gene and the genotypes of the major gene can be observed, the effect of themajor gene can be estimated and tested. In reality, the genotypes of a major gene cannot be observed. We normally evaluate acandidate gene whose genotypes can be measured using a particular molecular technique. We may have some reason to believe that the gene has a function on the variation of aquantitative trait. We can even evaluate a DNA marker whose genotypes are known but with unknown function on the trait. If this DNA marker is closely linked to amajor gene, the effect of the gene can also be estimated and tested through the marker. In either case, major gene analysis means estimation and test of the effect of an observedMendelian locus on a quantitative trait.


Major Gene Wald Test Dominance Effect Estimate Regression Coefficient Noncentrality Parameter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Shizhong Xu
    • 1
  1. 1.Department of Botany and Plant SciencesUniversity of CaliforniaRiversideUSA

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