Mechanotransduction of Shear-stress at the Mitochondria
Endothelial cells in situ experience a variety of physical forces caused by hemodynamics. Tensile stress (a perpendicular force of pressure and stretch) affects mostly the smooth muscle cells, and shear-stress (a tangential, frictional force) affects specifically the endothelial cells.
KeywordsMitochondrial Membrane Potential Pulmonary Artery Endothelial Cell Nitric Oxide Generation Pulmonary Microvascular Endothelial Cell Physiol Genomic
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