Mitochondria pp 169-181 | Cite as

Mechanotransduction of Shear-stress at the Mitochondria

  • Abu-Bakr Al-Mehdi
Part of the Advances in Biochemistry in Health and Disease book series (ABHD, volume 2)


Endothelial cells in situ experience a variety of physical forces caused by hemodynamics. Tensile stress (a perpendicular force of pressure and stretch) affects mostly the smooth muscle cells, and shear-stress (a tangential, frictional force) affects specifically the endothelial cells.


Mitochondrial Membrane Potential Pulmonary Artery Endothelial Cell Nitric Oxide Generation Pulmonary Microvascular Endothelial Cell Physiol Genomic 
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© Springer Science+Business Media, LLC 2007

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  • Abu-Bakr Al-Mehdi

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