Long-Term Morbidity of PCOS

  • Ricardo Azziz
Part of the Endocrine Updates book series (ENDO, volume 27)

Polycystic ovary syndrome, economic burden, healthcare cost, diabetes mellitus, cardiovascular disease, dyslipidemia, metabolic syndrome, endometrial cancer The polycystic ovary syndrome (PCOS) results in a number of immediate and long-term morbidities that are associated with a significant impact on quality of life and on economic costs. Immediate morbidities include menstrual dysfunction and abnormal uterine bleeding, subfertility and infertility, and androgen excess-related dermatologic abnormalities including hirsutism, acne, and androgenic alopecia, and an increased risk of obstetrical complications such as pregnancy-induced hypertension and gestational diabetes. However, PCOS is also associated with an increased risk of various other long-term complications or morbidities including cancer, type 2 diabetes mellitus (DM), the metabolic syndrome (MS), and possibly cardiovascular disease (CVD).


Metabolic Syndrome Endometrial Cancer Obstet Gynecol Polycystic Ovary Syndrome PCOS Patient 


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Copyright information

© Springer 2007

Authors and Affiliations

  • Ricardo Azziz
    • 1
  1. 1.Dept. of Ob/Gyn and Center for Androgen Related DisordersCedars-Sinai Medical CenterLos AngelesUSA

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