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Candidate gene, association, linkage, single nucleotide polymorphism, haplotype Polycystic ovary syndrome (PCOS) is considered a common, complex genetic disorder, as are conditions such as schizophrenia, asthma, and type 2 diabetes. Such common diseases, including PCOS, appear to have a complex, multifactorial etiology, wherein a variety of predisposing genes, not just one gene, interact with environmental and lifestyle factors to produce disease. Studies in families demonstrated the heritable nature of PCOS itself as well as the component phenotypes of PCOS. This has led to a large number of population studies attempting to discover genes that influence PCOS using the candidate gene approach.

Keywords

Androgen Receptor Polycystic Ovary Syndrome Haplotype Block Candidate Gene Approach Androgen Receptor Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2007

Authors and Affiliations

  • Mark O. Goodarzi
    • 1
  1. 1.Center for Androgen Related DisordersCedars-Sinai Medical CenterLos AngelesUSA

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