Pediatric Brain Metastasis from Extraneural Malignancies: A Review

  • Stewart Goldman
  • María E. Echevarría
  • Jason Fangusaro
Part of the Cancer Treatment and Research book series (CTAR, volume 136)


Brain metastasis is a well described and common complication in adult patients with cancer. It is estimated that between 25–40% of all adults with malignancies will develop brain metastasis [1–4]. This is particularly common in patients with melanoma, lung cancer, breast cancer and gastrointestinal tract neoplasms [5, 6]. In pediatric patients with solid tumors, however, the incidence of brain metastases is exceedingly rare. Most of the recent literature suggests that the overall incidence of brain metastases in pediatric oncology patients ranges from 1–10% [1–4].


Brain Metastasis Clin Oncol Pediatric Oncology Central Nervous System Metastasis Rhabdoid Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Stewart Goldman
    • 1
  • María E. Echevarría
    • 1
  • Jason Fangusaro
    • 1
  1. 1.Division of Hematology/Oncology and Stem Cell TransplantationChildren’s Memorial HospitalChicagoUSA

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