SPECT–CT Fusion Imaging Radionuclide Lymphoscintigraphy: Potential for Limb Lymphedema Assessment and Sentinel Node Detection In Breast Cancer
Radionuclide lymphoscintigraphy (RNL) has progressively superseded lymphangiography and may be considered as the most advanced method for the assessment of the limb lymphatic system (1, 2).As a safe, noninvasive, and physiological method, RNL is commonly used in lymphology for the evaluation of limb lymphedemas and in oncology for the detection of the sentinel node (SN) (3, 4).However, conventional planar imaging sometimes failed to preoperatively identify the exact localization of the detected lymph nodes (5). Since 2000 (6), hybrid cameras combining a dual head gamma camera with a low-dose radiograph tube mounted on the same gantry were developed, and image fusion has been successfully introduced in clinical practice.We report our experience of this new imaging method in lymphology and oncology, particularly for the SN detection in patients with breast cancer.
KeywordsSentinel Node Sentinel Node Mapping Popliteal Node Sentinel Node Detection Dual Head Gamma Camera
Unable to display preview. Download preview PDF.
- 1.Pecking AP, Cluzan RV, Desprez-Curely JP, Guérin P.: (1986) Functional study of the limb lymphatic system. Phlebology 1, 129–133.Google Scholar
- 2.Pecking AP, Cluzan RV, Desprez-Curely JP, Guérin P.: (1986) Indirect lymphoscintigraphy in patients with limb edemas. Phlebology 1, 215–217.Google Scholar
- 3.Monon DL, Wen DR, Wong JH, et al: (1992) Technical details of intraoperative lymphatic mapping for early Stage melanoma. Arch Surg 127:392–399.Google Scholar
- 4.Krag DN, Weaver DL, Alex JC, et al: (1993) Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg OncoI2:335–340.Google Scholar
- 13.Lerman H, Metser U.l, Lievshitz G, et al: (2006) lymphoscintigraphic sentinel node identification in patients with breast cancer: the role of SPECT–CT Eur Nucl Med Mol Imaging 33:329–337.Google Scholar