Overview and Pathology of Gastric Cancer

  • Pelayo Correa
  • M. Constanza Camargo
  • M. Blanca Piazuelo


For most of the twentieth century, gastric cancer was the major cancer burden worldwide. Its etiology and pathogenesis were obscure. Several events have changed that outlook, and currently, it ranks in the second place of mortality from cancer, after lung cancer. A gradual decline in the incidence of gastric cancer has been taking place for several decades, first seen in more affluent societies and then in other countries. The reasons for this decline are not entirely clear. However, it has coincided with several societal changes. Improvement in economic parameters in many populations was reflected in better home sanitation and better general nutrition. Fresh fruits and vegetables became available year round because of new technologies in home refrigeration and transportation. Other changes in dietary practices, such as the decrease in the intake of salt may also be linked to the decrease in gastric cancer incidence. Another relevant event was the development of the technology...


Gastric Cancer Pylorus Infection Intestinal Metaplasia Gastric Carcinogenesis Gastric Cancer Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media, LLC 2009

Authors and Affiliations

  • Pelayo Correa
    • 1
  • M. Constanza Camargo
    • 1
  • M. Blanca Piazuelo
    • 1
  1. 1.Division of Gastroenterology, Department of MedicineVanderbilt University Medical SchoolNashvilleUSA

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