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Silver as a Disinfectant

  • Nadia Silvestry-Rodriguez
  • Enue E. Sicairos-Ruelas
  • Charles P. Gerba
  • Kelly R. Bright
Chapter
Part of the Reviews of Environmental Contamination and Toxicology book series (RECT, volume 191)

Abstract

The antimicrobial effects of silver (Ag) have been recognized for thousands of years. In ancient times, it was used in water containers (Grier 1983) and to prevent putrefaction of liquids and foods. In ancient times in Mexico, water and milk were kept in silver containers (Davis and Etris 1997). Silver was also mentioned in the Roman pharmacopoeia of 69 b.c. (Davis and Etris 1997).

Keywords

Water Distribution System Cool Tower Free Chlorine Silver Sulfadiazine Drinking Water Disinfection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Albright LJ, Wentworth W, Wilson EM (1972) Technique for measuring metallic salt effects upon the indigenous heterotrophic microflora of a natural water. Water Res 6:1589–1596.CrossRefGoogle Scholar
  2. Anonymous (2006) Australian pesticides and veterinary medicines authority. http://www.apvm.gov.au/qa/poolspa_Q&A.shtml. Retrieved Feb. 1, 2006.
  3. Antelman MS (1992) Anti-pathogenic multivalent silver molecular semiconductors. Precious Metals 16:141–149.Google Scholar
  4. Armon R, Laot N, Lev O, Shuval H, Fattal B (2000) Controlling biofilm formation by hydrogen peroxide and silver combined disinfectant. Water Sci Technol 42:187–192.Google Scholar
  5. Auer J, Berent R, Ng CK, Punzengruber C, Mayr H, Lassnig E, Schwarz C, Puschmann R, Hartl P, Eber B (2001) Early investigation of silver-coated Silzone heart valves prosthesis in 126 patients. J Heart Valve Dis 10:717–723.Google Scholar
  6. Beer CW, Guilmartin LE, McLoughlin TF, White TJ (1999) Swimming pool disinfection. J Environ Health 61:9–13.Google Scholar
  7. Bell FA (1991) Review of effects of silver impregnated carbon filters on microbial water quality. J Am Water Works Assoc 83:74–76.Google Scholar
  8. Bellantone M, Williams HD, Hench LL (2002) Broad-spectrum bactericidal activity of Ag2O-doped bioactive glass. Antimicrob Agents Chemother 46:1940–1945.CrossRefGoogle Scholar
  9. Bentham RH, Broadbent CR (1993) A model for autumn outbreaks of Legionnaires’ disease associated with cooling-towers, linked to system operation and size. Epidemiol Infect 111:287–295.Google Scholar
  10. Blaker JJ, Boccaccini AR, Nazhat SN (2005) Thermal characterizations of silver-containing bioactive glass-coated sutures. J Biomater Appl 20:81–98.CrossRefGoogle Scholar
  11. Blanc DS, Carrara P, Zanetti G, Francioli P (2005) Water disinfection with ozone, copper and silver ions, and temperature increase to control Legionella: seven years of experience in a university teaching hospital. J Hosp Infect 60:69–72.CrossRefGoogle Scholar
  12. Borgmann SR (2003) Comparative assessment of different biocides in swimming pool water. Int Biodeterior Biodegrad 51:291–297.CrossRefGoogle Scholar
  13. Brady MJ, Lisay CM, Yurkovetskiy AV, Sawan SP (2003) Persistent silver disinfectant for the environmental control of pathogenic bacteria. Am J Infect Control 31:208–214.CrossRefGoogle Scholar
  14. Bragg PD, Rainnie DJ (1973) The effect of silver ions on the respiratory chain of Echerichia coli. Can J Microbiol 20:883–889.Google Scholar
  15. Breiman RF, Cozen W, Fields BS, Mastro TD, Carr SJ, Spika JS, Mascola L (1990) Role of air sampling in investigation of an outbreak of Legionnaires’ disease associated with exposure to aerosols from an evaporative condensor. J Infect Dis 161:1257–1261.Google Scholar
  16. Bright KR, Gerba CP, Rusin PA (2002) Rapid reduction of Staphylococcus aureus populations on stainless steel surfaces by zeolite ceramic coatings containing silver and zinc ions. J Hosp Infect 52:307–309.CrossRefGoogle Scholar
  17. Broadbent CR (1993) Legionella in cooling towers: practical research, design, treatment, and control guidelines. In: Barbaree JM, Breiman RF, Dufour AP (eds) Legionella: Current Status and Emerging Perspectives. American Society for Microbiology, Washington, DC, pp 217–222.Google Scholar
  18. Brown CM, Nuorti PJ, Breiman RF, Hathcock L, Fields BS, Lipman HB, Llewellyn GC, Hofmann J, Cetron M (1999) A community outbreak of Legionnaires’ disease linked to hospital cooling towers; an epidemiological method to calculate dose of exposure. Int J Epidemiol 28:353–359.CrossRefGoogle Scholar
  19. Butkus MA, Labare MP, Starke JA, Moon K, Talbot M (2004) Use of aqueous silver to enhance inactivation of coliphage MS-2 by UV disinfection. Appl Environ Microbiol 70:2848–2853.CrossRefGoogle Scholar
  20. Cassells JM, Yahya MT, Gerba CP, Rose JB (1995) Efficacy of a combined system of copper and silver and free chlorine for inactivation of Naegleria fowleri amoebas in water. Water Sci Technol 31:119–122.CrossRefGoogle Scholar
  21. CDC (Centers for Disease Control and Prevention) (1994) Legionnaires’ disease associated with cooling-towers. MMWR 43:491–493, 499.Google Scholar
  22. Chopra H (2007) The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern? J Antimicrob Chemother Feb 19, 2007 (Epub ahead of print).Google Scholar
  23. Cicalini S, Palmieri F, Petrosillo N (2004) Clinical review: new technologies for prevention of intravascular catheter-related infections. Crit Care 8:157–162.CrossRefGoogle Scholar
  24. Cowan MM, Abshire KZ, Houk SL, Evans SM (2003) Antimicrobial efficacy of a silver-zeolite matrix coating on stainless steel. J Ind Microbiol Biotechnol 30:102–106.Google Scholar
  25. Craun GF (1988) Surface water supplies and health. J Am Water Works Assoc 80:40–52.Google Scholar
  26. Darouiche RO (1999) Anti-infective efficacy of silver-coated medical prostheses. Clin Infect Dis 29:1371–1377.CrossRefGoogle Scholar
  27. Davis RI, Etris SF (1997) Development and functions of silver in water-purification and disease-control. Catalysis Today 36:107–114.CrossRefGoogle Scholar
  28. Deshpande LM, Chopade BA (1994) Plasmid mediated silver resistance in Acinetobacter baumannii. Biometals 7:49–56.CrossRefGoogle Scholar
  29. Dibrov P, Dzioba J, Gosink KK, Hase CC (2002) Chemiosmotic mechanism of antimicrobial activity of Ag+ in Vibrio cholerae. Antimicrob Agents Chemother 46:2668–2670.CrossRefGoogle Scholar
  30. Efrima S, Bronk BV (1998) Silver colloids impregnating or coating bacteria. J Phys Chem B 102:5947–5950.CrossRefGoogle Scholar
  31. Environmental Protection Agency (2002) National Secondary Drinking Water Regulations. http://www.epa.gov/safewater/mcl.html. Retrieved July 7, 2006.
  32. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO (2000) A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res 52:662–668.CrossRefGoogle Scholar
  33. Fliermans CB, Cherry WB, Orrison LH, Smith SJ, Tison DL, Pope DH (1981) Ecological distribution of Legionella pneumophila. Appl Environ Microbiol 41:9–16.Google Scholar
  34. Foegeding PM, Busta FF (1991) Chemical food preservatives. In: Block SS (ed) Disinfection, Sterilization, and Preservation, 4th Ed. Lea & Febiger, Philadelphia, p 842.Google Scholar
  35. Fox CL, Modak SM (1974) Mechanisms of silver sulfadiazine action on burn wound infections. Antimicrob Agents Chemother 5:582–588.Google Scholar
  36. Furr JR, Russell AD, Turner TD, Andrews A (1994) Antibacterial activity of Actisorb Plus, Actisorb and silver nitrate. J Hosp Infect 27:201–208.CrossRefGoogle Scholar
  37. Galeano B, Korff E, Nicholson WL (2003) Inactivation of vegetative cells, but not spores, of Bacillus anthracis, B. cereus, and B. subtilis on stainless steel surfaces coated with an antimicrobial silver-and zinc-containing zeolite formulation. Appl Environ Microbiol 69:4329–4331.CrossRefGoogle Scholar
  38. Gentry H, Cope S (2005) Using silver to reduce catheter-associated urinary tract infections. Nurs Stand 19:51–54.Google Scholar
  39. George N, Faoagali J, Muller M (1997) Silvazine (silver sulfadiazine and chlorhexidine) activity against 200 clinical isolates. Burns 23:493–495.CrossRefGoogle Scholar
  40. Ghandour W, Hubbard JA, Diestrung J, Hughes MN, Poole PK (1988) The uptake of silver ions by Escherichia coli K12: toxic effects and interaction with copper ions. Appl Microbiol Biotechnol 28:559–565.CrossRefGoogle Scholar
  41. Goddard PA, Bull TA (1989) Accumulation of silver by growing and non-growing populations of Citrobacter intermedius B6. Appl Microbiol Biotechnol 31:314–319.Google Scholar
  42. Grier N (1983) Silver and its compounds. In: Block SS (ed) Disinfection, Sterilization, and Preservation, 3rd Ed. Lea & Febiger, Philadelphia, pp 375–389.Google Scholar
  43. Gupta A, Maynes M, Silver S (1998) Effects of halides on plasmid-mediated silver resistance in Escherichia coli. Appl Environ Microbiol 64:5042–5045.Google Scholar
  44. Han J, Duan S, Yang Q, Gao C, Zhang B, He H, Dong X (2005) Efficient and quick inactivation of SARS coronavirus and others microbes exposed to the surfaces of some metals catalysts. Biomed Environ Sci 18:176–180.Google Scholar
  45. Heggers J, Goodheart RE, Washington J, McCoy L, Carino E, Dang T, Edgar P, Maness C, Chinkes D (2005) Therapeutic efficacy of three silver dressings in an infected animal model. J Burn Care Rehabil 26:53–56.CrossRefGoogle Scholar
  46. Heining CF Jr (1993) Catalyst-assisted oxidative sanitation. Ozone Sci Eng 12:533.Google Scholar
  47. Hotta M, Nakamima H, Yamamoto K, Aono M (1998) Antibacterial temporary filling materials: the effect of adding various ratios of Ag-Zn-zeolite. J Oral Rehabil 25:485–489.CrossRefGoogle Scholar
  48. Ibarluzea J, Moreno B, Zigorraga C, Castilla T, Martinez M, Santamaria J (1998) Determinants of the microbiological water quality of indoor swimming-pools in relation to disinfection. Water Res 32:865–871.CrossRefGoogle Scholar
  49. Innes ME, Umraw N, Fish JS, Gomez M, Cartotto RC (2001) The use of silver coated dressings on donor site wounds: a prospective, controlled matched pair study. Burns 27:621–627.CrossRefGoogle Scholar
  50. Inoue Y, Hoshino M, Takahashi H, Noguchi T, Murata T, Kanzaki Y, Hamashima H, Sasatsu M (2002) Bactericidal activity of Ag-zeolite mediated by reactive oxygen species under aerated conditions. J Inorg Biochem 92:37–42.CrossRefGoogle Scholar
  51. Ionescu A, Payne N, Fraser AG, Giddings J, Grunkemeier GL, Butchart EG (2003) Incidence of embolism and paravalvar leak after St Jude Silzone valve implantation: experience from the Cardiff Embolic Risk Factor Study. Heart 89:1055–1061.CrossRefGoogle Scholar
  52. Isenberg SJ (1990) The dilemma of neonatal ophthalmic prophylaxis. West J Med 153:190–191.Google Scholar
  53. Kadar M, Janossy L, Nagy G, Takatsy ZS, Koller M, Simon M, Pohl Ö (1993) Antiviral effect of a new disinfectant containing a silver complex and hydrogen peroxide as active agents. Wien Mitteil Wasser-Abwasser-Gewaesser 112: 62–64.Google Scholar
  54. Kawahara K, Tsuruda K, Morishita M, Uchida M (2000) Antibacterial effect of silver-zeolite on oral bacteria under anaerobic conditions. Dent Mater 16:452–455.CrossRefGoogle Scholar
  55. Kebabjian RS (1995) Disinfection of public pools and management of fecal accidents. J Environ Health 58:8–12.Google Scholar
  56. Kim H, Shim J, Lee S (2002) Formation of disinfection by-products in chlorinated swimming pool water. Chemosphere 46:123–130.CrossRefGoogle Scholar
  57. Kim J, Cho M, Oh B, Choi S, Yoon J (2004) Control of bacterial growth in water using synthesized inorganic disinfectant. Chemosphere 55:775–780.CrossRefGoogle Scholar
  58. Kim TN, Feng QL, Kim JO, Wu J, Wang H, Chen GC, Cui FZ (1998) Antimicrobial effects of metal ions (Ag+,Cu2+, Zn2+) in hydroxyapatite. J Mater Sci Mater Med 9:129–134.CrossRefGoogle Scholar
  59. Klueh U, Wagner V, Kelly S, Johnson A, Bryers JD (2000) Efficacy of silver-coated fabric to prevent bacterial colonization and subsequent device-based biofilm formation. J Biomed Mater Res 53:621–631.CrossRefGoogle Scholar
  60. Krause GA (1928) Neue Wege zur Wasserterilisierung. Bermann, München.Google Scholar
  61. Landeen LK, Yahya MT, Gerba CP (1989) Efficacy of copper and silver ions and reduced levels of free chlorine in inactivation of Legionella pneumophila. Appl Environ Microbiol 55:3045–3050.Google Scholar
  62. Li XZ, Nikaido H, Williams KE (1997) Silver-resistant mutants of Escherichia coli display active efflux of Ag+ and are deficient in porins. J Bacteriol 179:6127–6132.Google Scholar
  63. Liau SY, Read DC, Pugh WJ, Furr JR, Russell AD (1997) Interaction of silver-nitrate with readily identifiable groups: relationship to the antibacterial action of silver ions. Lett Appl Microbiol 25:279–283.CrossRefGoogle Scholar
  64. Liedberg H, Lundeberg T, Ekman P (1990) Refinements in the coating of urethral catheters reduces the incidence of catheter-associated bacteriuria. An experimental and clinical study. Eur Urol 17:236–240.Google Scholar
  65. Lin YS, Stout JE, Yu VL, Vidic RD (1998) Disinfection of water distribution systems for Legionella. Semin Respir Infect 13:147–159.Google Scholar
  66. Lin YS, Vidic RD, Stout JE, Yu VL (2002) Negative effect of high pH on biocidal efficacy of copper and silver ions in controlling Legionella pneumophila. Appl Environ Microbiol 68:2711–2715.CrossRefGoogle Scholar
  67. Liu Z, Stout JE, Tedesco L, Boldin M, Hwang C, Diven WF, Yu VL (1994) Controlled evaluation of copper-silver ionization in eradicating Legionella pneumophila from a hospital water distribution system. J Infect Dis 169:919–922.Google Scholar
  68. Lundeberg T (1986) Prevention of catheter-associated urinary-tract infections by use of silver-impregnated catheters. Lancet 2:1031.CrossRefGoogle Scholar
  69. Manal MG, Mayo MS, May LL, Simmons RB, Ahearn DG (1996) In vitro evaluation of the efficacy of a silver-coated catheter. Curr Microbiol 33:1–5.CrossRefGoogle Scholar
  70. Martinez SS, Alvarez AG, Esteban M (2004) Electrolytically generated silver and copper ions to treat cooling water: an environmentally friendly novel alternative. Int J Hydrogen Energy 29:921–932.CrossRefGoogle Scholar
  71. Matsumura Y, Yoshikata K, Kunisaki S, Tsuchido T (2003) Mode of bactericidal action of silver zeolite and its comparison with that of silver nitrate. Appl Environ Microbiol 69:4278–4281.CrossRefGoogle Scholar
  72. Mietzner S, Schwille RC, Farley A, Wald ER, Ge JH, States SJ, Libert T, Wadowsky RM, Miuetzner S (1997) Efficacy of thermal treatment and copper-silver ionization for controlling Legionella pneumophila in high-volume hot water plumbing systems in hospitals. Am J Infect Control 25:452–457.CrossRefGoogle Scholar
  73. Modak SM, Fox CL Jr (1973) Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa. Biochem Pharmacol 22:2391–2404.CrossRefGoogle Scholar
  74. Modak SM, Sampath L, Fox CL Jr (1988) Combined topical use of silver sulfadiazine and antibiotics as a possible solution to bacterial resistance in burn wounds. J Burn Care Rehabil 9:359–363.CrossRefGoogle Scholar
  75. Moudgal CJ, Lipscomb JC, Bruce RM (2000) Potential health effects of drinking water disinfection by-products using quantitative structure toxicity relationship. Toxicology 147:109–131.CrossRefGoogle Scholar
  76. Nover L, Scharf KD, Neuman D (1983) Formation of cytoplasmic heat shock protein granules in tomato cell cultures and leaves. Mol Cell Biol 3:1648–1655.Google Scholar
  77. Pedahzur R, Katzenelson D, Barnea N, Lev O, Shuval H, Ulitzur S (2000) The efficacy of long-lasting residual drinking water disinfectants based on hydrogen peroxide and silver. Water Sci Technol 42:293–298.Google Scholar
  78. Poon VK, Burd A (2004) In vitro cytotoxity of silver: implication for clinical wound care. Burns 30:140–147.CrossRefGoogle Scholar
  79. Quintavalla S, Vicini L (2002) Antimicrobial food packaging in meat industry. Meat Sci 62:373–380.CrossRefGoogle Scholar
  80. Rafter J, Grenier J, Denkewicz R (1999) US Patent #5,858,246. January 12, 1999; US Patent #5,935,609. August 10, 1999.Google Scholar
  81. Reasoner DJ, Blannon JC, Geldreich EE (1987) Microbial characteristics of third faucet point-of-use devices. J Am Water Works Assoc 79:60–66.Google Scholar
  82. Richards RM (1981) Antimicrobial action of silver nitrate. Microbios 31:83–91.Google Scholar
  83. Rohr U, Senger M, Selenka F, Turley R, Wilhelm M (1999) Four years of experience with silver-copper ionization for control of Legionella in a German university hospital hot water plumbing system. Clin Infect Dis 29:1507–1511.CrossRefGoogle Scholar
  84. Rohr U, Weber S, Selenka F, Wilhelm M (2000) Impact of silver and copper on the survival of amoebae and ciliated protozoa in vitro. Int J Hyg Environ Health 203:87–89.CrossRefGoogle Scholar
  85. Rosenkranz HS, Carr HS (1972) Silver sulfadiazine: effect on the growth and metabolism of bacteria. Antimicrob Agents Chemother 2:367–372.Google Scholar
  86. Rusin P, Gerba C (2001) Association of chlorination and UV irradiation to increasing antibiotic resistance in bacteria. Rev Environ Contam Toxicol 171:1–52.Google Scholar
  87. Rusin P, Bright K, Gerba C (2003) Rapid reduction of Legionella pneumophila on stainless steel with zeolite coatings containing silver and zinc ions. Lett Appl Microbiol 36:69–72.CrossRefGoogle Scholar
  88. Russell AD, Hugo WB (1994) Antimicrobial activity and action of silver. Prog Med Chem 31:351–370.CrossRefGoogle Scholar
  89. Samuni A, Aronovitch J, Chevio M, Czapski G (1984) In: Rottilio G, Bannister JV (eds) Life Chemistry Reports (Supplement), 2nd Ed. Harwood Academic, New York, pp 39–47.Google Scholar
  90. Schreurs WJ, Rosenberg H (1982) Effect of silver ions on transport and retention of phosphate by Escherichia coli. J Bacteriol 152:7–13.Google Scholar
  91. Shakibaie MR, Kapadnis BP, Dhakephalker P, Chopade BA (1999) Removal of silver from photographic wastewater effluent using Acinetobacter baumannii BL54. Can J Microbiol 45:995–1000.CrossRefGoogle Scholar
  92. Silver S (2003) Bacterial silver resistance: molecular biology and uses and misuses of silver compounds. FEMS Microbiol Rev 27:341–353.CrossRefGoogle Scholar
  93. Singer M (1990) The role of antimicrobial agents in swimming pools. Int Biodeterior 26:159–168.CrossRefGoogle Scholar
  94. Slawson RM, Lee H, Trevors JT (1990) Bacterial interactions with silver. Biol Metals 3:151–154.CrossRefGoogle Scholar
  95. Slawson RM, Van Dyke MI, Lee H, Trevors JT (1992) Germanium and silver resistance, accumulation, and toxicity in microorganisms. Plasmid 27:72–79.CrossRefGoogle Scholar
  96. Solioz M, Odermatt A (1995) Copper and silver transport by CopB-ATPase in membrane vesicles of Enterococcus hirae. J Biol Chem 270:9217–9221.CrossRefGoogle Scholar
  97. Spacciapoli P, Buxton D, Rothstein D, Friden P (2001) Antimicrobial activity of silver nitrate against periodontal pathogens. J Periodontal Res 36:108–113.CrossRefGoogle Scholar
  98. Starodub ME, Trevors JT (1990) Silver accumulation and resistance in Escherichia coli R1. J Inorg Biochem 39:317–325.CrossRefGoogle Scholar
  99. Stout JE, Yu VL (1997) Legionellosis. N Engl J Med 337:682–687.CrossRefGoogle Scholar
  100. Stout JE, Yu VL (2003) Experiences of the first 16 hospitals using copper-silver ionization for Legionella control: implications for the evaluation of other disinfection modalities. Infect Control Hosp Epidemiol 24:563–568.CrossRefGoogle Scholar
  101. Stout JE, Lin YS, Goetz AM, Muder RR (1998) Controlling Legionella in hospital water systems: experience with the superheat-and-flush method and coppersilver ionization. Infect Control Hosp Epidemiol 19:911–914.Google Scholar
  102. Straub TM, Gerba CP, Zhou X, Price R, Yahya MT (1995) Synergistic inactivaction of Escherichia coli and MS-2 coliphage by chloramine and cupric chloride. Water Res 29:811–818.CrossRefGoogle Scholar
  103. Takai KT, Ohtsuka T, Senda Y, Nakao M, Yamamoto K, Matsuoka-Junji J, Hirai Y (2002) Antibacterial properties of antimicrobial-finished textile products. Microbiol Immunol 46:75–81.Google Scholar
  104. Thurman RB, Gerba CP (1989) The molecular mechanisms of copper and silver ion disinfection of bacteria and viruses. CRC Crit Rev Environ Control 18:295–315.CrossRefGoogle Scholar
  105. Tzagoloff H, Pratt D (1964) The initial steps in infection with coliphage M13. Virology 24:372–380.CrossRefGoogle Scholar
  106. Uchida M (1995) Antimicrobial zeolite and its application. Chem Ind 46:48–54.Google Scholar
  107. Ulkur E, Oncul O, Karagoz H, Celikoz B, Cavuslu S (2005) Comparison of silvercoated dressing (Acticoat), chlorhexidine acetate 0.5% (Bactigrass), and silver sulfadiazine 1% (Silverdin) for topical antibacterial effect in Pseudomonas aeruginosa-contaminated, full-skin thickness burn wounds in rats. J Burn Care Rehabil 26:430–433.CrossRefGoogle Scholar
  108. Von Gunten U, Driedger A, Gallard H, Salhi E (2001) By-products formation during drinking water disinfection: a tool to assess disinfection efficiency? Water Res 35:2095–2099.CrossRefGoogle Scholar
  109. Wahlberg V (1982) Reconsideration of Credé prophylaxis. A study of maternity and neonatal care. Acta Paediatr Scand Suppl 295:1–73.Google Scholar
  110. Water Quality Association (2001) Use/Purchase of Home Water Treatment Systems. National Consumer Water Quality Survey, Naperville, IL.Google Scholar
  111. Williams RL, Grashoff GJ, Williams DF (1989) The biocompatibility of silver. Crit Rev Biocompat 5:221–243.Google Scholar
  112. Wood JM (1984) Microbiological strategies in resistance to metal ion toxicity. In: Sigel H (ed) Metal Ions in Biological Systems, vol 18. Marcel Dekker, New York, pp 333–351.Google Scholar
  113. World Health Organization (1996) Guidelines for Drinking-Water Quality, 2nd Ed. WHO, Geneva, Switzerland.Google Scholar
  114. Yahya MT, Landeen LK, Messina MC, Kutz SM, Schulze R, Gerba CP (1990) Disinfection of bacteria in water systems by using electrolytically generated copper: silver and reduced levels of free chlorine. Can J Microbiol 36:109–116.Google Scholar
  115. Yahya MT, Straub TM, Gerba CP (1992) Inactivation of coliphage MS-2 and poliovirus by copper, silver and chlorine. Can J Microbiol 38:430–435.CrossRefGoogle Scholar
  116. Yoshida K, Tanagawa M, Matsumoto S, Yamada T, Atsuta M (1999) Antibacterial activity of resin composites with silver-containing materials. Eur J Oral Sci 107:290–296.CrossRefGoogle Scholar
  117. Zacheus OM, Martikainen PJ (1994) Occurrence of Legionellae in hot water distribution systems of Finnish apartment buildings. Can J Microbiol 40:993–999.CrossRefGoogle Scholar

Copyright information

© Springer 2007

Authors and Affiliations

  • Nadia Silvestry-Rodriguez
    • 1
  • Enue E. Sicairos-Ruelas
    • 2
  • Charles P. Gerba
    • 2
  • Kelly R. Bright
    • 2
  1. 1.Department of Agricultural and Biosystems EngineeringUniversity of ArizonaTucsonUSA
  2. 2.Department of Soil, Water and Environmental ScienceUniversity of ArizonaTucsonUSA

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