Neuroimmune Activation in Sleep Apnea

  • Paul J. Mills
  • Michael G. Ziegler
  • Joel E. Dimsdale


Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder, characterized by repeated disruptions of breathing during sleep. The sleep fragmentation and the accompanying hypoxemia lead to many negative consequences including cardiovascular diseases, cognitive impairment, daytime sleepiness, fatigue, and depressive symptoms (Parish and Somers 2004; Reimer and Flemons 2003). Originally viewed as an interesting but rare malady, OSA is now recognized as a common disorder that is associated with major morbidity and mortality (Newman et al. 2001).


Obstructive Sleep Apnea Sleep Apnea Continuous Positive Airway Pressure Obstructive Sleep Apnea Syndrome Obstructive Sleep Apnea Patient 
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© Springer 2007

Authors and Affiliations

  • Paul J. Mills
  • Michael G. Ziegler
  • Joel E. Dimsdale

There are no affiliations available

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