It is becoming increasingly clear that epigenetic silencing of tumor suppressor genes plays a causative role in human carcinogenesis. Epigenetic silencing involves changes in DNA cytosine methylation as well as chromatin structural changes which act to reinforce gene inactivation and thus the progression of tumors.
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Jones, P.A. (2007). Short Abstracts – Session IV. In: Fagagna, F.d.d., Chiocca, S., McBlane, F., Cavallaro, U. (eds) Advances in Molecular Oncology. Advances In Experimental Medicine And Biology, vol 604. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-69116-9_11
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DOI: https://doi.org/10.1007/978-0-387-69116-9_11
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