Congenital Optic Disc Anomalies

  • Michael C. Brodsky


Congenital anomalies of the optic disc underlie many cases of decreased vision, strabismus, and nystagmus in childhood. A comprehensive evaluation necessitates an understanding of the ophthalmoscopic features, associated neuro-ophthalmologic findings, pathogenesis, and appropriate ancillary studies for each anomaly. The subclassification of different forms of “colobomatous” defects on the basis of their ocular and systemic associations has further refined our ability to predict the likelihood of associated central nervous system (CNS) anomalies solely on the basis of the appearance of the optic disc. The widespread availability of modern neuroimaging has refined our ability to identify subtle associated CNS anomalies and to prognosticate neurodevelopmental and endocrinological problems. Genetic analysis has now advanced our understanding of some anomalies.


Optic Disc Lamina Cribrosa Myelinated Nerve Fiber Optic Nerve Hypoplasia Serous Macular Detachment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Michael C. Brodsky
    • 1
  1. 1.Professor of Ophthalmology and NeurologyMayo ClinicRochesterUSA

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