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Pancreas

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Acute Care Surgery

Abstract

You are asked to evaluate a patient who was admitted for alcohol-induced pancreatitis. The patient has had a smoldering course despite aggressive resuscitation and is, currently, febrile and toxic while receiving broad-spectrum antimicrobial therapy. Physical examination demonstrates midepigastric tenderness on moderate palpation. Computed tomography scan findings are consistent for necrotizing pancreatitis. The white blood cell count has increased from 12,000 to 16,000 over the past 48 hours.Which of the following is the most prudent management plan at this time?

  1. (A)

    Continued medical management

  2. (B)

    Peritoneal lavage

  3. (C)

    Computed tomography—directed biopsy of the necrotic tissue for confirmation of infectious etiology

  4. (D)

    Celiotomy

  5. (E)

    Administration of octreotide

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References

  1. Kreel L, Sandin B. Changes in pancreatic morphology associated with aging. Gut 1973; 14:962.

    CAS  PubMed  Google Scholar 

  2. Baldwin WM. The pancreatic ducts in man, together with a study of the microscopical structure of the minor duodenal papilla. Anat Rec 1911; 5:197.

    Google Scholar 

  3. Anacker H. Radiological anatomy of the pancreas. In Anacker H, ed. Efficiency and Limits of Radiologic examination of the Pancreas. Acton, MA: Publishing Sciences Group, 1975.

    Google Scholar 

  4. Classen M, Koch H, Ruskin H, et al. Pancreatitis after endoscopic retrograde pancreatography (ERCP). Gut 1973; 14:431.

    CAS  PubMed  Google Scholar 

  5. Sivak MV, Sullivan BH. Endoscopic retrograde pancreatography: analysis of the normal pancreatogram. Am J Dig Dis 1976; 51:263.

    Google Scholar 

  6. Gross RE. Surgery of Infancy and Childhood. Philadelphia: WB Saunders, 1972.

    Google Scholar 

  7. Silen W. Surgical anatomy of the pancreas. Surg Clin North Am 1964; 44:1253.

    Google Scholar 

  8. Michels NA. Blood supply of the pancreas and duodenum. In Blood Supply Anatomy of the Upper Abdominal Organs with a Descriptive Atlas. Philadelphia: JB Lippincott, 1995: 236–247.

    Google Scholar 

  9. Child CG. The Hepatic Circulation and Portal Hypertension. Philadelphia: WB Saunders, 1954.

    Google Scholar 

  10. Gray SW, Skandalakis JE. Embriology for Surgeons. Philadelphia, 1972.

    Google Scholar 

  11. Baker RJ, Dippel WF, Freeark RJ, et al. The surgical significance of the trauma to the pancreas. Arch Surg 1963; 86:1038–1044.

    CAS  PubMed  Google Scholar 

  12. Culotta RJ, Howard JM, Jordan GL. Traumatic injuries of the pancreas. Surgery 1956; 40:320–327.

    CAS  PubMed  Google Scholar 

  13. Jones RC, Shires GT. The management of pancreatic injuries. Arch Surg 1965; 90:502–508.

    CAS  PubMed  Google Scholar 

  14. Anane-Sefah J, Norton LW, Eiseman B. Operative choice and technique following pancreatic injury. Arch Surg 1975; 110:161–166.

    CAS  PubMed  Google Scholar 

  15. Babb J, Harmon H. Diagnosis and management of pancreatic trauma. Am Surg 1976; 6:390–394.

    Google Scholar 

  16. Campbell RC, Kennedy T. The management of pancreatic and pancreaticoduodenal injuries. Br J Surg 1980; 67:845–850.

    CAS  PubMed  Google Scholar 

  17. Nilson E, Norby S, Skulman S, et al. Pancreatic trauma in a defined population. Acta Chir Scand 1986; 152:647–651.

    Google Scholar 

  18. Feliciano DV, Martin TD, Cruse PA, et al. Management of combined pancreaticoduodenal injuries. Ann Surg 1987; 205:673–680.

    CAS  PubMed  Google Scholar 

  19. Leppaniemi A, Haapiainen R, Kiviluoto T, et al. Pancreatic trauma: acute and late manifestations. Br J Surg 1988; 75:165–167.

    CAS  PubMed  Google Scholar 

  20. Lewis G, Knottenbelt JD, Jriege JE. Conservative surgery for trauma to the pancreatic head: is it safe? Injury 1991; 3722:372–374.

    Google Scholar 

  21. Gentilello LM, Cortez V, Buechter K, et al. Whipple procedure for trauma: is duct ligation a safe alternative to pancreaticojejunostomy? J Trauma 1991; 31:661–668

    CAS  PubMed  Google Scholar 

  22. Madiba TE, Mokoena TR. Favorable prognosis after surgical drainage of gunshot, stab or blunt trauma of the pancreas. Br J Surg 1995; 82:1236–1239.

    CAS  PubMed  Google Scholar 

  23. Asensio JA, Petrone P, Roldan G, et al. Operative management and outcome in 214 pancreatic injuries. Trauma surgical procedure and AAST-OIS predict morbidity and mortality. In press.

    Google Scholar 

  24. Stone HH, Stowers KB, Shippey SH. Injuries to the pancreas. Arch Surg 1962; 85:187–192.

    Google Scholar 

  25. Salyer K, McClelland R. Pancreaticoduodenectomy for trauma. Arch Surg 1967; 95:636–639.

    CAS  PubMed  Google Scholar 

  26. Werschky LR, Jordan GL. Surgical management of traumatic injuries of the pancreas. Am J Surg 1968; 116:768–772.

    CAS  PubMed  Google Scholar 

  27. Foley WJ, Gaines RD, Fry WJ. Pancreatoduodenectomy for severe trauma to the head of the pancreas and the associated structures: report of three cases. Ann Surg 1969; 170:759–765.

    CAS  PubMed  Google Scholar 

  28. Sheldon GF, Cohn LH, Blaisdell FW. Surgical treatment of pancreatic trauma. J Trauma 1970; 10:795–800.

    CAS  PubMed  Google Scholar 

  29. Bach RD, Frey CF. Diagnosis and treatment of pancreatic trauma. Am J Surg 1971; 121:20–29.

    CAS  PubMed  Google Scholar 

  30. White PH, Benfield JR. Amylase in the management of pancreatic trauma. Arch Surg 1972; 105:158–162.

    CAS  PubMed  Google Scholar 

  31. Salam A, Warren WD, Kalser M, et al. Pancreatoduodenectomy for trauma: clinical and metabolic studies. Ann Surg 1972; 175:663–669.

    CAS  PubMed  Google Scholar 

  32. Yellin AE, Vecchione TR, Donovan AJ. Distal pancreatectomy for pancreatic trauma. Am J Surg 1972; 124:135:42.

    CAS  PubMed  Google Scholar 

  33. Anderson CB, Connors JP, Mejia DC, et al. Drainage methods in the treatment of pancreatic injuries. Surg Gynecol Obstet 1974; 138:587–590.

    CAS  PubMed  Google Scholar 

  34. Lowe RJ, Saletta JD, Moss GS. Pancreatoduodenectomy for penetrating trauma. J Trauma 1977; 17:732–741.

    CAS  PubMed  Google Scholar 

  35. Jones RC. Management of pancreatic trauma. Ann Surg 1978; 187:555–564.

    CAS  PubMed  Google Scholar 

  36. Graham JM, Mattox KL, Vaughan GD III, et al. Combined pancreatoduodenal injuries. J Trauma 1979; 19:340–346.

    CAS  PubMed  Google Scholar 

  37. Majesky JA, Tyler G. Pancreatic trauma. Am Surg 1980; 10:593–596.

    Google Scholar 

  38. Stone HH, Fabian TC, Satiani B, et al. Experiences in the management of pancreatic trauma. J Trauma 1981; 21:257–262.

    CAS  PubMed  Google Scholar 

  39. Berni GA, Bandyk DF, Oreskovich MR, et al. Role of intraoperative pancreatography in patients with injury to the pancreas. Am J Surg 1982; 143:602–605.

    CAS  PubMed  Google Scholar 

  40. Cogbill TH, Moore EE, Kashuk JL. Changing trends in the management of pancreatic trauma. Arch Surg 1982; 117:722–758.

    CAS  PubMed  Google Scholar 

  41. Fitzgibbons TK, Yellin AE, Maruyama MM, Donovan AJ. Management of the transected pancreas following distal pancreatectomy. Sur Gynecol Obstet 1982; 154:225–231.

    CAS  Google Scholar 

  42. Oreskovich MR, Carrico CJ. Pancreaticoduodenectomy for trauma: a viable option? Am J Surg 1984; 147:618–623.

    CAS  PubMed  Google Scholar 

  43. Sims EH, Mandal AU, Schlater T, et al. Factors affecting outcomes in pancreatic trauma. J Trauma 1984; 24:125–128.

    CAS  PubMed  Google Scholar 

  44. Wynn M, Hill DH, Miller DR, et al. Management of pancreatic and duodenal trauma. Am J Surg 1985; 150:327–332.

    CAS  PubMed  Google Scholar 

  45. Nowak MM, Baringer DC, Ponsky JL. Pancreatic injuries: effectiveness of debridement and drainage for nontransecting injuries. Am Surg 1986; 52:599–602.

    CAS  PubMed  Google Scholar 

  46. Gorenstein A, O’Halpin D, Wesson DE, et al. Blunt injury to the pancreas in children: selective management based on ultrasound. J Pediatr Surg 1987; 22:1110–1116.

    CAS  PubMed  Google Scholar 

  47. Pachter HL, Hofstetter SR, Liang HG, et al. Traumatic injuries to the pancreas: the role of distal pancreatectomy with splenic preservation. J Trauma 1989; 29:1352–1355.

    CAS  PubMed  Google Scholar 

  48. Fabian TC, Kudsk KA, Croce MA, et al. Superiority of closed suction drainage for pancreatic trauma: a randomized prospective study. Ann Surg 1990; 211:724–730.

    CAS  PubMed  Google Scholar 

  49. Flynn WJ, Cryer HG, Richardson JD. Reappraisal of pancreatic and duodenal injury management based on injury severity. Arch Surg 1990; 125:1539–1541.

    PubMed  Google Scholar 

  50. Ivatury RR, Nallathambi M, Rao P, et al. Penetrating pancreatic injuries: analysis of 103 consecutive cases. Am Surg 1990; 56:90–95.

    CAS  PubMed  Google Scholar 

  51. Cogbill TH, Moore EE, Morris JA, et al. Distal pancreatectomy for trauma: a multicenter experience. J Trauma 1991; 31:1600–1606.

    CAS  PubMed  Google Scholar 

  52. Voeller GR, Mangiante EC, Fabian TC. The effect of a trauma system on the outcome of patients with pancreatic trauma. Arch Surg 1991; 126:578–580.

    CAS  PubMed  Google Scholar 

  53. Buck JR, Sorensen VJ, Fath JJ, et al. Severe pancreaticoduodenal injuries: the effectiveness of pyloric exclusion with vagotomy. Am Surg 1992; 58:557–561.

    CAS  PubMed  Google Scholar 

  54. Rosen MA, McAninch JW. Management of combined renal and pancreatic trauma. J Urol 1994; 152:22–25.

    CAS  PubMed  Google Scholar 

  55. Delcore R, Satuffer JS, Thomas JH, et al. The role of pancreatogastrostomy following pancreatoduodenectomy for trauma. J Trauma 1994; 37:395–400.

    CAS  PubMed  Google Scholar 

  56. Craig MH, Talton DS, Hauser CJ, et al. Pancreatic injuries from blunt trauma. Am Surg 1995; 61:125–128.

    CAS  PubMed  Google Scholar 

  57. Degiannis E, Levy RD, Potokar LT, et al. Distal pancreatectomy for gunshot injuries of the distal pancreas. Br J Surg 1995; 82:1240–1242.

    CAS  PubMed  Google Scholar 

  58. Degiannis E, Levy RD, Velamhos G, et al. Gunshot injuries of the head of the pancreas: conservative approach. World J Surg 1996; 20:68–72.

    CAS  PubMed  Google Scholar 

  59. Smith DR, Stanley RJ, Rue LW III. Delayed diagnosis of pancreatic transaction after blunt abdominal trauma. J Trauma 1996; 40:1009–1013.

    CAS  PubMed  Google Scholar 

  60. Akhrass R, Yaffe MB, Brandt CP, et al. Pancreatic trauma: a ten-year multi-institutional experience. Am Surg 1997; 63:598–604.

    CAS  PubMed  Google Scholar 

  61. Farrell RJ, Krige EJ, Bornman PC, et al. Operative strategies in pancreatic trauma. Br J Surg 1996; 83:934–937.

    CAS  PubMed  Google Scholar 

  62. Patton J Jr, Lyden SP, Croce MA, et al. Pancreatic trauma: a simplified management guideline. J Trauma 1997; 43:234–241.

    PubMed  Google Scholar 

  63. Timbelake GA. Blunt pancreatic trauma: experience at a rural referral center. Am Surg 1997; 63:282–286.

    Google Scholar 

  64. Young P Jr, Meredith JW, Baker CC, et al. Pancreatic injuries resulting from penetrating trauma: a multiinstitutional review. Am Surg 1998; 64:838–844.

    PubMed  Google Scholar 

  65. Eastlick L, Fogler R, Shaftan GW. Pancreaticoduodenectomy for trauma: delayed reconstruction: a case report. J Trauma 1990; 30:503–505.

    CAS  PubMed  Google Scholar 

  66. Asensio J, Demetriades D, Berne J, et al. A unified approach to the surgical exposure of pancreatic and duodenal injuries. Am J Surg 1997; 174:54–60.

    CAS  PubMed  Google Scholar 

  67. Asensio JA, Demetriades D, Hanpeter DE, et al. Management of pancreatic injuries. Curr Probl Surg 1999; 36(5):325–420.

    CAS  PubMed  Google Scholar 

  68. Asensio JA, Petrone P, Roldan G, et al. Pancreatic and duodenal injuries: complex and lethal. Scand J Surg 2002; 91(1):81–86.

    CAS  PubMed  Google Scholar 

  69. Kasugai T, Kuno N, Kobayashi S, et al. Endoscopic pancreatocholangiography, I: the normal endoscopic pancreatocholangiogram. Gastroenterology 1972; 63:217.

    CAS  PubMed  Google Scholar 

  70. Classen M, Koch H, Ruskin H, et al. Pancreatitis after endoscopic retrograde pancreatography (ERCP). Gut 1973; 14:431.

    CAS  PubMed  Google Scholar 

  71. Asensio JA. Operative pancreatograms at 2 AM? In Critical Decision Points in Trauma Care. Proceedings of postgraduate course. Am Coll Surg 1992; 5:55–57.

    Google Scholar 

  72. Moore EE, Cogbill TH, Malangoni MA, et al. Organ injury scaling, II: pancreas, duodenum, small bowel, colon and rectum. J Trauma 1990; 30:1427.

    CAS  PubMed  Google Scholar 

  73. Whipple AO, Parson WB, Mullins CR. Treatment of carcinoma of the ampulla of Vater. Ann Surg 1935; 102:763–779.

    CAS  PubMed  Google Scholar 

  74. Howell JF, Burrus GR, Jordan GL. Surgical management of pancreatic injuries. J Trauma 1961; 1:32–40.

    Google Scholar 

  75. Thal AP, Wilson RF. A pattern of severe blunt trauma to the region of the pancreas. Surg Gynecol Obstet 1964; 119:773–778.

    CAS  PubMed  Google Scholar 

  76. Halgrimson CG, Trimble C, Gale S, et al. Pancreaticoduodenectomy for traumatic lesions. Am J Surg 1969; 118:877–882.

    CAS  PubMed  Google Scholar 

  77. Walter RL, Gaspard DJ, German TD. Traumatic pancreatitis. Am J Surg 1966; 111:364–368.

    Google Scholar 

  78. Thompson RJ, Hindshaw DB. Pancreatic trauma. Ann Surg 1966; 163:153–160.

    PubMed  Google Scholar 

  79. Sawyers JL, Carlisle BB, Sawyers JE. Management of pancreatic injuries. South Med J 1967; 60:382–386.

    CAS  PubMed  Google Scholar 

  80. Wilson RF, Tagett JP, Pucelik JP, et al. Pancreatic trauma. J Trauma 1967; 7:643–651.

    CAS  PubMed  Google Scholar 

  81. Brawley RK, Cameron JL, Zuidema G. Severe upper abdominal injuries treated by pancreaticoduodenectomy. Surg Gynecol Obstet 1968; 126:516–522.

    CAS  PubMed  Google Scholar 

  82. Pantazelos HH, Kerhulas AA, Byrne JJ. Total pancreaticoduodenectomy for trauma. Ann Surg 1969; 170:1016–1020.

    CAS  PubMed  Google Scholar 

  83. Gibbs BF, Crow JL, Rupnik EJ. Pancreatoduodenectomy for blunt pancreatoduodenal injury. J Trauma 1970; 10:702–705.

    PubMed  Google Scholar 

  84. Nance FC, De Loach DH. Pancreaticoduodenectomy following abdominal trauma. J Trauma 1971; 11:577.

    CAS  PubMed  Google Scholar 

  85. Jones RC, Shires T. Pancreatic trauma. Arch Surg 1971: 102:424–430.

    CAS  PubMed  Google Scholar 

  86. Smith A, Wolverton W, Wiechert R III, et al. Operative management of pancreatic and duodenal injuries. J Trauma 1971; 11:570–576.

    PubMed  Google Scholar 

  87. Anderson CB, Weisz D, Rodger MR, et al. Combined pancreaticoduodenal trauma. Am J Surg 1973; 125:530–534.

    CAS  PubMed  Google Scholar 

  88. Owens M, Wolfman E Jr. Pancreatic trauma: management and presentation of a new technique. Surgery 1973; 73:881–886.

    CAS  PubMed  Google Scholar 

  89. Steele M, Sheldon GF, Blaisdell FW. Pancreatic injuries. Arch Surg 1973; 106:544–549.

    CAS  PubMed  Google Scholar 

  90. Sturm JT, Quattlebaum FW, Mowlem A, et al. Patterns of injury requiring pancreatoduodenectomy. Surg Gynecol Obstet 1973; 137:629–632.

    CAS  PubMed  Google Scholar 

  91. Yellin AE, Rossof L. Pancreatoduodenectomy for combined pancreatoduodenal injuries. Arch Surg 1975; 110:1117–1183.

    Google Scholar 

  92. Chamber RT, Norton L, Hinchey EJ. Massive right upper quadrant intra-abdominal injury requiring pancreaticoduodenectomy and partial hepatectomy. J Trauma 1975; 15:714–719.

    Google Scholar 

  93. Balasegaram M. Surgical management of pancreatic trauma. Am J Surg 1976; 131:536–540.

    CAS  PubMed  Google Scholar 

  94. Heitsch RC, Knutson CO, Fulton RL, et al. Delineation of critical factors in the treatment of pancreatic trauma. Surgery 1976; 80:523–529.

    CAS  PubMed  Google Scholar 

  95. Karl HW, Chandler JG. Mortality and morbidity of pancreatic injury. Am J Surg 1977; 134:549–554.

    CAS  PubMed  Google Scholar 

  96. Hagan WV, Urdaneta LF, Stephenson SE. Pancreatic injury. South Med J 1978; 171:892–894.

    Google Scholar 

  97. Stone HH, Fabian TC. Management of duodenal wounds. J Trauma 1979; 19:334–339.

    CAS  PubMed  Google Scholar 

  98. Levinson MA, Peterson SR, Sheldon GF, et al. Duodenal trauma: experience of a trauma center. J Trauma 1982; 24:475–480.

    Google Scholar 

  99. Henarejos A, Cohen DM, Moosa AR. Management of pancreatic trauma. Ann R Coll Surg Engl 1983; 65:297–300.

    CAS  PubMed  Google Scholar 

  100. Adkins RB Jr, Keyser JE III. Recent experience with duodenal trauma. Am Surg 1984; 5:121–231.

    Google Scholar 

  101. Moore JB, Moore EE. Changing trends in the management of combined pancreatoduodenal injuries. World J Surg 1984; 8:791–797.

    CAS  PubMed  Google Scholar 

  102. Fabian TC, Mangiante EC, Millis M. Duodenal rupture due to blunt trauma: a problem in diagnosis. South Med J 1984; 77:1078–1082.

    CAS  PubMed  Google Scholar 

  103. Donahue JH, Crass RA, Trunkey DD. The management of duodenal and other small intestinal trauma. World J Surg 1985; 9:904–913.

    Google Scholar 

  104. Jones RC. Management of pancreatic trauma. Am J Surg 1985; 150:698–704.

    CAS  PubMed  Google Scholar 

  105. Ivatury RR, Nallathambi M, Gaudino J, et al. Penetrating duodenal injuries: analysis of 100 consecutive cases. Am J Surg 1985; 2:153–158.

    Google Scholar 

  106. Smego DR, Richardson JD, Flint LM. Determinants of outcome in pancreatic trauma. J Trauma 1985; 25:771–776.

    CAS  PubMed  Google Scholar 

  107. Walker ML. Management of pancreatic trauma: concepts and controversy. J Natl Med Assoc 1986; 78:1177–1183.

    CAS  PubMed  Google Scholar 

  108. Melissas J, Baart GD, Mannel A. Pancreaticoduodenectomy for pancreatic trauma. S Afr Med J 1987; 71:32–34.

    Google Scholar 

  109. McKone TK, Bursch LR, Scholten DJ. Pancreaticoduodenectomy for trauma: a life-saving procedure. Am Surg 1988; 54:361–364.

    CAS  PubMed  Google Scholar 

  110. Heimansohn DA, Canal DF, McCarthy MC, et al. The role of pancreaticoduodenectomy in the management of traumatic injuries to the pancreas and duodenum. Am Surg 1990; 56:511–514.

    CAS  PubMed  Google Scholar 

  111. Asensio JA, Petrone P, Roldan G, et al. Role of the pancreaticoduodenectomy: a rare procedure for the management of complex pancreaticoduodenal injuries. J Am Coll Surg 2003; 197:937–942.

    PubMed  Google Scholar 

  112. Glancy KE. Review of pancreatic trauma. West J Med 1989; 151:45–51.

    CAS  PubMed  Google Scholar 

  113. Graham JM, Mattox KL, Vaughan GD III, et al. Traumatic injuries of the pancreas. Am J Surg 1978; 136:744–748.

    CAS  PubMed  Google Scholar 

  114. Balasegaram M. Surgical management of pancreatic trauma. Curr Probl Surg 1979; 16:1–59.

    CAS  PubMed  Google Scholar 

  115. Buchler M, Friess H, Klempa I, et al. Role of the octreotide in the prevention of postoperative complications following pancreatic resections. Am J Surg 1992; 163: 126–131.

    Google Scholar 

  116. Kudsk KA, Temizer D, Ellison EC, et al. Post-traumatic pancreatic sequestration: recognition and treatment. J Trauma 1986; 26:320–324.

    CAS  PubMed  Google Scholar 

  117. Werner J, Uhl W, Buchles M, eds. Cameron’s Current Surgical Therapy, 8th ed. Philadelphia: Elsevier/Mosby, 2005: 456–469.

    Google Scholar 

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Asensio, J.A., Petrone, P., Britt, L.D. (2007). Pancreas. In: Britt, L.D., Trunkey, D.D., Feliciano, D.V. (eds) Acute Care Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-69012-4_32

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