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How Does Optical Coherence Tomography Work? Basic Principles

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Retinal Angiography and Optical Coherence Tomography

Optical coherence tomography (OCT) (Stratus OCT, Carl Zeiss Meditec, Inc., Dublin, CA) (Fig. 10.1) is a commercially available computer-assisted precision optical instrument that generates cross-sectional images (tomograms) of ocular structures with close to 10-μm axial resolution.1 This technology is evolving, and its axial resolution has been reported to be as high as 3 μm in laboratory settings (ultrahigh-resolution OCT).23 Optical coherence tomography is analogous to B-mode ultrasound, except that it uses light rather than sound. Unlike ultrasound, OCT does not require contact with the tissue examined.

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Arevalo, J.F., Krivoy, D., Fernandez, C.F. (2009). How Does Optical Coherence Tomography Work? Basic Principles. In: Arevalo, J.F. (eds) Retinal Angiography and Optical Coherence Tomography. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68987-6_10

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  • DOI: https://doi.org/10.1007/978-0-387-68987-6_10

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