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Gynecology

  • Ahmad Wagih Abdel Halim
Chapter

Estrogen

  • Natural:
    1. 1.

      Estrone (E1): Estrogen of menopause.

       
    2. 2.

      Estradiol (E2): Estrogen of reproductive age.

       
    3. 3.

      Estriol (E3): Estrogen of pregnancy.

       
  • Synthetic: Multiple forms and dosages. Note that Diethylstilbestrol (D.E.S) is no longer used due to its dangerous effects, e.g., Vaginal adenosis and clear cell adenocarcinoma; also incompetent cervix and abortion.

  • Sources:
    1. 1.

      Graafian follicle: Source of E2 during first half of menstrual cycle.

       
    2. 2.

      Corpus luteum: Source of E2 during second half of menstrual cycle.

       
    3. 3.

      Placenta: Source of E3 during pregnancy.

       
    4. 4.

      Adipose tissue: Peripheral conversion of androgens to estrogen by aromatase enzyme.

       
  • Actions: Refer to Table 4.1

Table 4.1

Actions of estrogen and progesterone.

 

Estrogen

Progesterone

Breasts

• Develop duct system

• Develop acinar system

• Increase fat deposition

• Blocks prolactin action on the breast

Kidneys

• Increase salt and water retention

• Induces diuresis

Pituitary

• Feedback inhibition of FSH & LH

• Feedback...

Keywords

Endometrial Cancer Luteinizing Hormone Clinical Picture Follicle Stimulate Hormone Germ Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.McLaren Regional Medical CenterFlintUSA

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