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Immunology

  • Ahmad Wagih Abdel (Halim)
Chapter

Immunity

  • Active: Generated by the body after exposure to an infection or a vaccine, e.g., antigens

  • Passive: Donated to the body transplacentally, or through injection of antibodies

Lymphoid Organs

  • It is where lymphocytes develop, and they are divided into:
    1. 1.
      Central: Where cells are formed:
      • T lymphocytes are formed in the Thymus.

      • B lymphocytes are formed in the liver during the fetal period, and in the bone marrow in adults.

       
    2. 2.

      Peripheral: Where cells are expressed. This takes place in the spleen, lymph nodes, tonsils, and Peyer’s patches.

       
  • Cell-mediated immunity (CMI): It is the job of T lymphocytes, natural killer (NK) cells, and macrophages, which are destined to kill the organism and its aberrant host cells.

  • Humoral immunity: It is the job of B lymphocytes, which produce antibodies.

Major Histocompatibility Complex (MHC)

  • The MHC is a cluster of genes found in every human and animal cell. It is known as human leukocyte antigen (HLA) in humans, and is located on chromosome 6.

  • Function...

Keywords

Major Histocompatibility Complex Human Leukocyte Antigen Chronic Granulomatous Disease Hereditary Angioedema Leukocyte Adhesion Deficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.McLaren Regional Medical CenterFlintUSA

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