Optic Disc Tumors

  • Jane W. Chan


Retinoblastoma affects the sensory retina and is the most common intraocular malignant tumor of childhood that occasionally may extend into the optic nerve. Up to 30% of cases are bilateral. The incidence of retinoblastoma is about 1 in 20,000 live births in the United States. 1 Seventy percent of all retinoblastomas are unilateral and 30% are bilateral. Bilateral cases are transmitted in an autosomal dominant manner with incomplete penetrance. 2 Only 10%–15% of unilateral cases are hereditary. 3 The average age at presentation in bilateral cases is about 10 months and in unilateral cases 21 months. 2


Optic Nerve Retinal Pigment Epithelium Optic Disc Tuberous Sclerosis Tuberous Sclerosis Complex 
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© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Jane W. Chan
    • 1
  1. 1.Ophthalmology and NeurologyUniversity of Kentucky College of MedicineLexingtonUSA

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