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Compressive and Infiltrative Optic Neuropathies

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Optic Nerve Disorders

Abstract

In contrast to the meningiomas from intracranial extension or the ectopic orbital ones, primary optic nerve sheath meningiomas (ONSM) arise from the intraorbital optic nerve sheath and grow circumferentially around the optic nerve to result in an optic neuropathy by interfering with axonal transport and pial blood supply to the nerve. They constitute 1% to 2% of all meningiomas and account for one-third of all primary optic nerve tumors. They are also the second most common optic nerve tumor after glioma.1 Only 10% of ONSM arise from the orbit, compared to 90% from intracranial extension. More than 90% of ONSM develop in the orbital optic nerve rather than in the canalicular portion.2

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  1. Ophthalmology and Neurology, University of Kentucky College of Medicine, Lexington, KY, USA

    Jane W. Chan MD (Assciate Professor)

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Chan, J.W. (2007). Compressive and Infiltrative Optic Neuropathies. In: Optic Nerve Disorders. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68979-1_4

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