Abstract
Optical coherence tomography (OCT) is an evolving technology that provides noninvasive imaging of tissues. It uses low coherence interferometry to produce cross-sectional images based on the optical scattering of light, 1 similar to ultrasound. Since its introduction into the ophthalmology clinic in the 1990s, optical coherence tomography has become a standard tool for the evaluation of ophthalmic disease. Although its main use was initially for retinal disease and glaucoma, OCT now has a niche in neuro-ophthalmic evaluation. It is mainly useful to rule in occult retinal disease when the etiology of visual loss is unclear, but it is also used to evaluate and follow up abnormalities of the retinal nerve fiber layer (RNFL), such as optic nerve edema and atrophy.2
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science 1991;254:1178–1181.
Hedges TR, Amaro-Quireza ML. Multifocal visual evoked potential, multifocal electroretinography, and optical coherence tomography in the diagnosis of subclinical loss of vision. Ophtalmol Clin N Am 2004;17:89–105.
Hee MR, Fujimoto JC, Ko T, et al. Interpretation of the optical coherence image. In: Schuman JS, Puliafito CA, Fujimoto JG, editors. Optical coherence tomography of ocular diseases. Thorofare, NJ: Slack; 2004.
Schuman JS, Pedut-Kloizman T, Herzmark E, et al. Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmology 1996;103:1889–1898.
Blumenthal EZ, Williams JM, Weinreb RN, et al. Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography. Ophthalmology 2000;107;2278–2282.
Budenz DL, Chang RT, Huang X, et al. Reproducibility of retinal nerve fiber thickness measurements using the stratus OCT in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 2005;46:2440–2443.
Olmedo M, Cadarso-Suarez C, Gomez-Ulla F, et al. Reproducibility of optic nerve head measurements obtained by optical coherence tomography. Eur J Ophthalmol 2005;15:486–492.
Schuman JS, Hee MR, Arya AV, et al. Optical coherence tomography: a new tool for glaucoma diagnosis. Curr Opin Ophthalmol 1995;6:89–95.
Hoye VJ, Berrocal AM, Hedges TR III, Amaro-Quireza ML. Optical coherence tomography demonstrates subretinal macular edema from papilledema. Arch Ophthalmol 2001;119:1287–1290.
Hedges TR III, Flattem NL, Bagga A. Vitreopapillary traction confirmed by optical coherence tomography. Arch Ophthalmol 2006;124:279–281.
Karam EZ, Hedges TR. Optical coherence tomography of the retinal nerve fibre layer in mild papilloedema and pseudopapilloedema. Br J Ophthalmol 2005;89:294–298.
Schuman JS, Hee MR, Puliafito CA, et al. Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. Arch Ophthalmol 1995;113:586–596.
Monteiro ML, Leal BC, Rosa AA, et al. Optical coherence tomography of axonal loss in band atrophy of the optic nerve. Br J Ophthalmol 2004;88:896–899.
Kanamori A, Nakamura M, Matsui N, et al. Optical coherence tomography detects characteristic nerve fiber layer thickness corresponding to band atrophy of the optic discs. Ophthalmology 2004;111:2278–2283.
Barboni P, Savini G, Valentino ML, et al. Retinal nerve fiber layer evaluation by optical coherence tomography in Leber’s hereditary optic neuropathy. Ophthalmology 2005;112:120–126.
Savini G, Barboni P, Valentino ML, et al. Retinal nerve fiber layer evaluation by optical coherence tomography in unaffected carriers with Leber’s hereditary optic neuropathy mutations. Ophthalmology 2005;112:127–131.
Zoulaman CI, Agarwal M, Sadun AA. Optical coherence tomography can measure axonal loss in patients with ethambutol induced optic neuropathy. Graefes Arch Clin Exp Ophthalmol 2005;5:410–416.
Fisher JB, Jacobs DA, Markowitz CE, et al. Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis. Ophthalmology 2006;113:324–332.
Hedges TR III. Optical coherence tomography inneuro-ophthalmology. In: Schuman JS, Puliafito CA, Fujimoto JG, editors. Optical coherence tomography of ocular diseases. Thorofare, NJ: Slack; 2004.
Roh S, Noecker RJ, Schuman JS, et al. Effect of optic nerve head drusen on nerve fiber layer thickness. Ophthalmology 1998;105:878–885.
Roh S, Noecker RJ, Schuman JS. Evaluation of coexistent optic nerve head drusen and glaucoma with optical coherence tomography. Ophthalmology 1997;104:1138–1144.
Unoki K, Ohba N, Hoyt WF. Optical coherence tomography of superior segmental optic hypoplasia. Br J Ophthalmol 2002;86:910–914.
Wakakura M, Ishikawa S. Central serous chorioretinopathy complicating systemic corticosteroid treatment. Br J Ophthalmol 1984;5:329–331.
Drexler W, Morgner U, Ghanta RK, et al. Ultra-high-resolution ophthalmic optical coherence tomography. Nat Med 2001;7:502–507.
Drexler W, Sattmann H, Hermann B, et al. Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography. Arch Ophthalmol 2003; 121:695–706.
Wojtkowski M, Bajraszewski T, Gorczynska I, et al. Ophthalmic imaging by spectral optical coherence tomography. Am J Ophthalmol 2004;138:412–419.
Wojtkowski M, Srinivasan V, Fujimoto JG, et al. Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography. Ophthalmology 2005;112:1734–1746.
Schmidt-Erfurth U, Leitgeb RA, Michels S, et al. Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases. Invest Ophthalmol Vis Sci 2005;46:3393–3402.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
RodrÃguez-Padilla, J.A., Hedges, T.R. (2007). Optical Coherence Tomography in Optic Nerve Disorders. In: Optic Nerve Disorders. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68979-1_10
Download citation
DOI: https://doi.org/10.1007/978-0-387-68979-1_10
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-68978-4
Online ISBN: 978-0-387-68979-1
eBook Packages: MedicineMedicine (R0)