Optic Neuritis

  • Jane W. Chan


Although neurologists usually diagnose and treat multiple sclerosis, the visual loss that often accompanies this disease often presents to an ophthalmologist or neuro-ophthalmologist for evaluation. It is an inflammation of one or both optic nerves resulting in (usually) temporary visual loss. It affects young to middle-aged adults between 16 and 55 years of age. The female-tomale ratio is 2:1. Children often are affected bilaterally, whereas adults are affected unilaterally. The annual incidence of acute optic neuritis has been estimated in population-based studies to be between 1 and 5 per 100,000.1,2 Clinically definite multiple sclerosis (CDMS) is apparent at the onset of optic neuritis in 15% to 20% of patients with optic neuritis; another 40% will later experience a multiple sclerosis attack.3 The clinical diagnosis and advances of understanding the pathogenesis and current recommended treatment of this disorder are outlined here.


Multiple Sclerosis Optic Nerve Optic Neuritis Optic Neuropathy Visual Evoke Potential 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Jane W. Chan
    • 1
  1. 1.Ophthalmology and NeurologyUniversity of Kentucky College of MedicineLexingtonUSA

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