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Complications of Regional Anesthesia pp 61–73Cite as

Local Anesthetic Toxicity

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Abstract

Effective regional block is not possible without the use of local anesthetics. Even though local anesthetics have been used for more than 115 years, details about balancing risks of their toxic effects with the benefits of their therapeutic effects remain poorly focused for many clinicians. In this chapter, the most frequent toxic effect of local anesthetics — local anesthetic systemic toxicity — will be covered, as will the less-frequent clinical situations of allergy to local anesthetics and myelotoxicity.

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Authors and Affiliations

  1. Department of Anesthesiology and Pain Medicine, M. D. Anderson Cancer Center, Houston, TX, USA

    David L. Brown MD (Edward Rotan Distinguished Professor and Chairman)

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  1. David L. Brown MD
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Editors and Affiliations

  1. Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada

    Brendan T. Finucane MB, BCh, BAO, FRCA, FRCPC (Professor) (Professor)

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Brown, D.L. (2007). Local Anesthetic Toxicity. In: Finucane, B.T. (eds) Complications of Regional Anesthesia. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68904-3_4

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  • DOI: https://doi.org/10.1007/978-0-387-68904-3_4

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  • Print ISBN: 978-0-387-37559-5

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