Acquired Ichthyosis, Acanthosis Nigricans, Palmar Hyperkeratosis


Serious systemic diseases, including visceral cancer, may be indirectly signaled by the development of distinctive cutaneous eruptions. Important aspects of these eruptions include development of the rash concurrent with the diagnosis of the neoplasm and the fact that the two entities, though individually uncommon, are commonly seen together and pursue a similar clinical course. The more important, albeit uncommon, dermatoses that develop in conjunction with visceral cancer involve disorders of the epithelium and entail alterations in keratinization. This chapter will deal with the clinical and pathologic attributes of acquired ichthyosis, acanthosis nigricans, and paraneoplastic palmar/plantar keratoderma as they relate to underlying malignancy.


Mycosis Fungoides Acanthosis Nigricans Underlying Malignancy Seborrheic Keratosis Palmoplantar Keratoderma 
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Acquired Ichthyosis

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© Springer Science+Business Media, LLC 2007

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