Advertisement

Neoplasms of the Joint

  • Andrew J. Cooper
  • James D. Reeves
  • Sean P. Scully

Abstract

  • The most common primary neoplasms of the joint are pigmented villonodular synovitis and synovial chondromatosis and a diagnosis is best made using magnetic resonance imaging (MRI).

  • Other primary lesions are rare and include lipoma arborescens, synovial hemangiomas, intracapsular chondromas, and synovial chondrosarcomas.

  • ■Secondary neoplasms of the joint are synovial sarcoma and giant cell tumors.

  • ■ The malignancies that metastasize to bone also may invade the articular space.

Keywords

Synovial Sarcoma Giant Cell Tumor Tendon Sheath Loose Body Synovial Chondromatosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Tyler WK, Vidal AF, Williams RJ, Healey JH. Pigmented villonodular synovitis. J AAOS 2006;14:376–385.Google Scholar
  2. 2.
    Rao AS, Vigorita VJ. Pigmented villonodular synovitis (giant cell tumor of the tendon sheath and synovial membrane): a review of eighty-one cases. J Bone Joint Surg Am 1984;66:76–94.PubMedGoogle Scholar
  3. 3.
    Granowitz SP, D’Antonio J, Mankin HL. The pathogenesis and long term end results of pigmented villonodular synovitis. Clin Orthop 1976;114:335–351.PubMedGoogle Scholar
  4. 4.
    Docken WP. Pigmented villonodular synovitis: a review with illustrative case reports. Semin Arthritis Rheum 1979;9:1–22.PubMedCrossRefGoogle Scholar
  5. 5.
    Dorwart RH, Genant HK, Johnston WH, Morris JM. Pigmented villonodular synovitis of synovial joints: clinical, pathologic, and radiologic features. AJR Am J Roentgenol 1984;143:877–885.PubMedGoogle Scholar
  6. 6.
    Bravo SM, Winalski CS, Weissman BN. Pigmented villonodular synovitis. Radiol Clin North Am 1996;34:311–326.PubMedGoogle Scholar
  7. 7.
    Byers PD, Cotton RE, Deacon OW, et al. The diagnosis and treatment of pigmented villonodular synovitis. J Bone Joint Surg Br 1968;50:290–305.PubMedGoogle Scholar
  8. 8.
    Flandry F, Hughston JC. Pigmented villonodular synovitis. J Bone Joint Surg Am 1987;69:942–949.PubMedGoogle Scholar
  9. 9.
    Flandry F, Hughston JC, Jacobsen KE, Barrack RL, McCann SB, Kurtz DM. Surgical treatment of diffuse pigmented villonodular synovitis of the knee. Clin Orthop 1994;300:183–192.PubMedGoogle Scholar
  10. 10.
    Wu KK, Ross PM, Guise ER. Pigmented villonodular synovitis: a clinical analysis of twenty-four cases treated at Henry Ford Hospital. Orthopedics 1980;3:751–758.Google Scholar
  11. 11.
    Jaffe HL. Tumor and tumorous conditions of the bone and joints. Philadelphia: Lea and Febiger; 1958.Google Scholar
  12. 12.
    Michael RH. Pigmented villonodular synovitis. Orthop Nurs 1997;16:66–68.PubMedCrossRefGoogle Scholar
  13. 13.
    Lewis RW. Roentgen diagnosis of pigmented villonodular synovitis and synovial sarcoma of knee joint. Radiology 1947;49:26.PubMedGoogle Scholar
  14. 14.
    Uchibori M, Nishida Y, Tabata I, et al. Expression of matrix metalloproteinases and tissue inhibitors of metal-loproteinases in pigmented villonodular synovitis suggests their potential for joint destruction. J Rheumatol 2004;31:110–119.PubMedGoogle Scholar
  15. 15.
    Schwartz HS, Unni KK, Pritcherd DJ. Pigmented villonodular synovitis. A retrospective review of affected large joints. Clin Orthop 1989;247:243–255.PubMedGoogle Scholar
  16. 16.
    Scott PM. Bone lesions in pigmented villonodular synovitis. J Bone Joint Surg Br 1968;50:306–311.PubMedGoogle Scholar
  17. 17.
    Cheng XG, You YH, Liu W, Zhao T, Qu H. MRI features of pigmented villonodular synovitis (PVNS). Clin Rheumatol 2004;23:31–34.PubMedCrossRefGoogle Scholar
  18. 18.
    Goldman AB, DiCarlo EF. Pigmented villonodular synovitis: diagnosis and differential diagnosis. Radiol Clin North Am 1988;26:1327–1347.PubMedGoogle Scholar
  19. 19.
    Jaffe HL, Lichtenstein L, Sutro CJ. Pigmented villonodular synovitis, bursitis, and tenosynovitis. Arch Pathol 1941; 31:731–765.Google Scholar
  20. 20.
    De Ponti A, Sansone V, Malchere M. Results of arthroscopic treatment of pigmented villonodular synovitis of the knee. Arthroscopy 2003;19:602–607.PubMedCrossRefGoogle Scholar
  21. 21.
    Blanco CE, Leon HO, Guthrie TB. Combined partial arthroscopic synovectomy and radiation therapy for diffuse pigmented villonodular synovitis of the knee. Arthroscopy 2001;17:527–531.PubMedCrossRefGoogle Scholar
  22. 22.
    Enneking WF. Clinical musculoskeletal pathology. 3rd ed. Gainesville, FL: University of Florida Press; 1990:243–250, 255-259, 312-317, 439-441.Google Scholar
  23. 23.
    Milgram JW. Synovial osteochondromatosis. J Bone Joint Surg Am 1977;59:792–801.PubMedGoogle Scholar
  24. 24.
    Trias A, Quintana O. Synovial chondrometaplasia: review of world literature and a study of 18 Canadian cases. Can J Surg 1976;19:151–158.PubMedGoogle Scholar
  25. 25.
    Coles MJ, Tara HH. Synovial chondromatosis: a case study and brief review. Am J Orthop 1997;26:37–40.PubMedGoogle Scholar
  26. 26.
    Crotty JM, Monu JU, Pope TL. Synovial osteochondromatosis. Radiol Clin North Am 1996;34:327–342.PubMedGoogle Scholar
  27. 27.
    Wuisman PI, Noorda RJ, Jutte PC. Chondrosarcoma secondary to chondromatosis. Report of two cases and a review of the literature. Arch Orthop Trauma Surg 1997; 116:307–311.PubMedCrossRefGoogle Scholar
  28. 28.
    Hopyan S, Nadesan P, Yu C, Wunder J, Alman BA. Dys-regulation of hedgehog signaling predisposes to synovial chondromatosis. J Pathol 2005;206:143–150.PubMedCrossRefGoogle Scholar
  29. 29.
    Laorr A, Helms CA. MRI of musculoskeletal masses. A practical text and atlas. New York: Igaku-Shoin; 1997:159–161, 275-280, 329-345.Google Scholar
  30. 30.
    Chen CY, Chen AC, Chang YH, Fu TS, Lee MS. Synovial chondromatosis of the hip: management with arthroscope-assisted synovectomy and removal of loose bodies: report of two cases. Chang Gung Med J 2003;26:208–214.PubMedGoogle Scholar
  31. 31.
    Fowble VA, Levy HJ. Arthroscopic treatment for synovial chondromatosis of the shoulder. Arthroscopy 2003;19:E2.PubMedCrossRefGoogle Scholar
  32. 32.
    Campanacci M. Bone and soft tissue tumors. New York: Springer-Verlag; 1981:99–135, 1109-1126, 1243-1252, 1289-1306.Google Scholar
  33. 33.
    Kaakaji Y, Valle DE, McCarthy KE, Nietzschman HR. Case of the day. Case 4: synovial Sarcoma. AJR Am J Roentgenol 1998;171:868–870.Google Scholar
  34. 34.
    Namba Y, Kawai A, Naito N, Morimoto Y, Hanakawa S, Inoue H. Intraarticular synovial sarcoma confirmed by SYT-SSX fusion transcript. Clin Orthop 2002:221–226.Google Scholar
  35. 35.
    Machen KS, Easley KA, Goldblum JR. Synovial sarcoma of the extremities. A clinicopathologic study of 34 cases, including semi-quantitative analysis of spindles, epithelial, and poorly differentiated areas. Am J Surg Pathol 1999; 23:268–275.PubMedCrossRefGoogle Scholar
  36. 36.
    Pretto D, Barco R, Rivera J, Neel N, Gustavson MD, Eid JE. The synovial sarcoma translocation protein SYT-SSX2 recruits beta-catenin to the nucleus and associates with it in an active complex. Oncogene 2006;25:3661–3669.PubMedCrossRefGoogle Scholar
  37. 37.
    Enzinger FM, Weiss SW. Soft tissue tumors. 2nd ed. St. Louis: Mosby; 1988:638–688, 861-881.Google Scholar

Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Andrew J. Cooper
    • 1
  • James D. Reeves
    • 2
  • Sean P. Scully
    • 2
  1. 1.Department of Orthopaedic SurgeryUniversity of MiamiMiamiUSA
  2. 2.Department of Orthopaedics, Miller School of MedicineUniversity of MiamiMiamiUSA

Personalised recommendations