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Storage and Deposition Diseases

  • Duncan A. Gordon

Abstract

  • Some unusual arthropathies are caused by deposition of normal material, such as metal ions, or storage of abnormal material, such as lipids.

  • Hemochromatosis, ochronosis, and Wilson’s disease are characterized by cellular deposition of the normal metal ions: iron, calcium, and copper, respectively.

  • ■ In Gaucher’s disease, Fabry’s disease, Farber’s disease, and multicentric reticulohistiocytosis, rheumatic manifestations result from cellular storage of abnormal lipids.

Keywords

Enzyme Replacement Therapy Fabry Disease Deposition Disease C282Y Mutation Homogentisic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Duncan A. Gordon
    • 1
    • 2
  1. 1.Toronto Western HospitalUniversity Health NetworkTorontoCanada
  2. 2.Department of MedicineUniversity of TorontoTorontoCanada

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