The metabolic myopathies are a heterogeneous group of diseases characterized by impaired skeletal muscle energy production.
Primary metabolic myopathies are associated with genetic defects in glycogen and lipid metabolism.
Secondary types occur with abnormal production of parathyroid, thyroid, and cortisol production and vitamin D defi ciency.
■ Symptoms occur mainly during or shortly after exercise and include pain, weakness, and cramping, and can result in myoglobinuria due to muscle necrosis.
KeywordsSerum Creatine Kinase Mitochondrial Myopathy Carnitine Level Metabolic Myopathy Acid Maltase
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