Protein Contact Map Prediction
Proteins are linear chains that fold into characteristic shapes and features. To understand proteins and protein folding, we try to represent the protein molecule in such a way that its features are easy to see and manipulate. A simple representation facilitates algorithm design for structure prediction. The simplicity of the threestate character string representation of secondary structure is part of the reason for secondary structure prediction receiving so much attention early in the era of computational biology. One-dimensional strings are easily understood, parsed, mined, and manipulated. But secondary structure alone does not tell us enough about the overall shapes and features of a protein.We need a simpleway to represent the overall tertiary structure of a protein.
KeywordsAssociation Rule Local Contact Correlate Mutation Residue Pair Residue Contact
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